Results 31 to 40 of about 6,035,856 (262)

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

FEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze, Stéphane Canaan, Alexandre Gouzy, Pierre Santucci   +3 more
wiley   +1 more source

Introduction About Child Health Status in India [PDF]

, 2017
Child health is a multifaceted problem which is directly linked to a large extent to mother’s health conditions, safe delivery conditions, socio-economic conditions of the family and the health care system.
Agarwal, R. (Rishu), Billaiya, R. (Roshni), Jain, A. (Anupam), Jain, P. (Paras)   +3 more
core   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

The Health Status of New Medicaid Enrollees Under Health Reform [PDF]

, 2010
Examines the demographic and health data of those newly eligible for Medicaid coverage, whether younger and healthier or older and less healthy than current enrollees, and how they will affect costs depending on participation ...
Genevieve M. Kenney, Jennifer E. Pelletier, John Holahan   +2 more
core  

Identification of novel small molecule inhibitors of ETS transcription factors

FEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla, Zary Forghany, Jin Ma, Johan G. Hollander, Ruta Nachane, Karoly Szuhai, Pancras C. W. Hogendoorn, Peter ten Dijke, Dipen Shah, David A. Baker   +9 more
wiley   +1 more source

The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum

FEBS Letters, EarlyView.
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti, Sebastian Obermaier, Dirk J. Slotboom, Bert Poolman   +3 more
wiley   +1 more source

How Engaged Are Consumers in Their Health and Health Care, and Why Does It Matter? [PDF]

, 2008
Summarizes findings on U.S. patients' ability to manage their health and health care by income level, education, Medicaid status, and health status. Examines access to care by level of engagement among the chronically ill.
Judith H. Hibbard, Peter J. Cunningham
core  

Assessing health and well-being among older people in rural South Africa [PDF]

, 2010
Background: The population in developing countries is ageing, which is likely to increase the burden of noncommunicable diseases and disability. Objective: To describe factors associated with self-reported health, disability and quality of life (QoL) of
Benjamin D. Clark, Case A, Cieza A, Collinson MA, Collinson MA, F. Xavier Gómez-Olivé, Hargreaves JR, Jasso G, Jelsma J, Kahn K, Kahn K, Kahn K, Kathleen Kahn, Lam D, Margaret Thorogood, Menken J, Min SK, Murray CJ, Nguyen N, Phaladze NA, Quinn TC, Reeve B, Schatz EJ, Stephen M. Tollman, Strong K, Tollman SM, United Nations Department of Economics and Social Affairs, Velkoff VA, Westaway MS, WHOQOL Group, WHOQOL Group, Wittenberg M, Zwang J   +32 more
core   +3 more sources

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

The Dynamics of Food Deprivation and Overall Health: Evidence from the Canadian National Population Health Survey [PDF]

The paper explores whether the responses to food deprivation questions on the longitudinal Canadian National Population Health Survey help explain the links between socio-economic status and health.
Logan McLeod, Michael R. Veall
core   +3 more sources