Results 111 to 120 of about 1,624,025 (308)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Poverty levels and children's health status: study of risk factors in an urban population of low socioeconomic level

open access: yesRevista de Saúde Pública, 1996
To test the hypothesis that the low socioeconomic population living is shanty towns in Porto Alegre presents different levels of poverty which are reflected on its health status, a cross-sectional study was designed involving 477 families living in Vila ...
Issler Roberto M.S.   +6 more
doaj  

Confiabilidad prueba-reprueba de la postura de balance unipodal de 10 segundos en adultos jóvenes de Palmira, Colombia

open access: yesMedUNAB
RESUMEN Introducción. La inestabilidad postural en apoyo unipodal es un factor asociado al riesgo de fragilidad y mortalidad en adultos mayores; sin embargo, el sedentarismo y la inactividad física en adultos jóvenes colombianos podrían anticipar ...
Samuel José Hernández-Almanza   +2 more
doaj   +1 more source

2015 Wisconsin Health Trends: Making Wisconsin the Healthiest State [PDF]

open access: yes, 2016
The Wisconsin State Health Plan for 2020 established a goal for all state residents to live longer and better. Progress toward this goal can be measured by monitoring health outcomes -- and the factors that contribute to those outcomes -- for the state's

core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Social heterogeneity in self-reported health status and measurement of inequalities in health [PDF]

open access: yes
This study aims to analyse the impact of the measurement of health status on socioeconomic inequalities in health. A MIMIC model with structural equations is used to create a latent variable of health status from four health indicators: self-assessed ...
Catherine Sermet   +3 more
core  

Health promotion indicators: current status, issues and problems [PDF]

open access: yes, 2017
This article describes the background to the current status of health promotion indicator research and defines the major issues and problems involved. It then discusses both of these areas in detail.
MCQUEEN, DAVID, NOACK, HORST
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Equity in the Utilisation of Hospital Inpatient Services in Ireland? An Improved Approach to the Measurement of Health Need [PDF]

open access: yes
The complex interweaving of public and private provision in Irish hospitals has led to concerns that hospital care is not available to all on the basis of need alone.
Richard Layte
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

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