Results 211 to 220 of about 1,506,645 (358)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Mental health disparities across demographic and social groups in Abu Dhabi. [PDF]

Discov Ment Health
Badri M, Khaili MA, Dhaheri HA, Yang G, Albahar M, Alrashdi A, Yaaqeib S, Alsawai A.   +7 more
europepmc   +1 more source

Characteristics of health behaviours and health status indicators among pregnant women in Slovenia

, 2017
Tina Kek, Nataša Karas Kuželički, Irena Mlinarič‐Raščan, Ksenija Geršak   +3 more
openalex   +2 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Clinical performance measures: The changing status of peritoneal dialysis11Note: The Centers for Medicare and Medicaid Services (CMS), formerly the Health Care Financing Administration (HCFA) ESRD Core Indicators Study, supplied the data described in this report. The interpretation and reporting of these data are the responsibility of the authors and are not an official policy or interpretation of the Centers for Medicare and Medicaid Services. [PDF]

, 2001
Michael J. Flanigan, Michael V. Rocco, Barbara F. Prowant, Pamela R. Frederick, Diane L. Frankenfield   +4 more
openalex   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Using an AI-powered Mobile Application Chatbot to Address Maternal Depression Indicators and Inquiries in the Perinatal and Postpartum Periods: A Multimethod Analysis. [PDF]

Inquiry
Peters CJ, Aldana Lainez V, Clark K, Jasczynski M, Nguyen QC, Norell EM.   +5 more
europepmc   +1 more source

The relationship between income, health insurance, and employment status as prognostic indicators of bladder cancer: A survival analysis

Wahjoe Djatisoesanto, Yufi Aulia Azmi, Ida Bagus Gde Tirta Yoga Yatindra   +2 more
openalex   +2 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Combination of partial least square structural equation modeling scheme of principal component analysis with importance performance analysis. [PDF]

MethodsX
Otok BW, Alfasanah Z, Aksioma DF.
europepmc   +1 more source