Results 241 to 250 of about 582,509 (334)

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

Molecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma, Sophia M. Orbach, Kate V. Griffin, Kathryn Kang, Yining Zhang, Rebecca S. Pereles, Ian A. Schrack, Guillermo Escalona, Jacqueline S. Jeruss, Lonnie D. Shea   +9 more
wiley   +1 more source

Physical Status of School Children as a Health Indicator in a Small Community (Part 3)

, 1967
H Kahyo, Masaharu Maeda
openalex   +2 more sources

Risk indicators for dental caries among preschoolers, school children/adolescents and adults in Nigeria: a scoping review. [PDF]

BMC Oral Health
Nnawuihe UC, Ehizele AO, Afolabi AO, Nwaokorie FO, Lusher J, Akinsolu FT, Salako AO, Ezechi OC, Foláyan MO.   +8 more
europepmc   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Exploratory social indicator model building and testing using multiple indicators within a block-recursive system: a study of the macrosociological determinants of health status

, 1977
Frank A. Fear
openalex   +1 more source

Association of immunonutritional indicators with all-cause mortality in adult stroke patients. [PDF]

Sci Rep
Deng K, Feng S, Cheng F, Zhang X, Li Y, Ju J, Wang Z, Wang P, Wang C.   +8 more
europepmc   +1 more source

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

Molecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci, Izzet Akiva, Yavuz Hakan Ozon, Hakan Berkil, Huseyin Karadayi, Omer Dizdar, Suayib Yalcin   +6 more
wiley   +1 more source

Research on the impact of multidimensional poverty in childhood on disability in middle-aged and older adult. [PDF]

Front Public Health
Xie R, Zhao F, Ding L, Dong H, Wu B.
europepmc   +1 more source

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source

Determinants of general health perception among individuals with chronic low back pain overtime: structural equation modeling. [PDF]

PLoS One
Eilayyan O, Enjalbert-Auneau L, Ahmed S.
europepmc   +1 more source