Results 261 to 270 of about 582,509 (334)

Comprehensive scoping review on adherence to 24-hour movement guidelines and socioeconomic indicators in children and adolescents. [PDF]

PLoS One
Gonçalves L, Zanlorenci S, Da Silva Almeida MF, Vanhelst J, Santos Silva DA.   +4 more
europepmc   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

Molecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed, Lucas Mani, Muhammad Bilal Mirza, Ashtyn McAdoo, Takahito Kondo, Hidenori Tanaka, Nicole Meeks, Eben Rosenthal, Marisa Hom   +8 more
wiley   +1 more source

Morphofunctional and psychophysiological body indicators in monitoring students’ health status, in view of their adjustment to academic environment

Oxana Anfinogenova, Hardeep Singh Deep, Dmitry Domenyuk, Gleb Ivchenko, Igor Rzhepakovsky   +4 more
openalex   +2 more sources

Associations of sarcopenia status and its components with the risk of developing functional disability in older Chinese adults: evidence from the China health and retirement longitudinal study. [PDF]

BMC Public Health
Hao Z, Haoxiang L, Shujun L.
europepmc   +1 more source

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

Molecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho, Yubin Hah, Eunsik Yun, Hye In Ka, Aram Lee, Sora Han, Dawn Lee, Sung Wook Kim, Jong Hoon Park, Byung Su Kwon, Young Yang, Jongmin Kim   +11 more
wiley   +1 more source

Association between eosinophil number and overweight status: a nonlinear, bidirectional study. [PDF]

Lipids Health Dis
Yue X, Wang C, Zhang X.
europepmc   +1 more source

Strategies to reduce the cancer burden and improve access to effective and affordable cancer interventions in Europe

Molecular Oncology, EarlyView.
Comprehensive cancer centre (CCCs) and CCCs of Excellence (CCCoE) integration in healthcare. Through outreach to surrounding community hospitals, CCCs enable wider access to top‐clinical cancer treatments and care, thereby facilitating the swift enrolment of patients into data‐rich clinical trials (PI‐initiated trials testing new concepts, drug ...
Anton Berns, Ulrik Ringborg, Julio Celis, Bengt Jönsson, Michael Baumann   +4 more
wiley   +1 more source

Ni justo ni legítimo: The role of social status and neoliberal context on perceived social justice in Latin America and its political consequences. [PDF]

Br J Soc Psychol
Solano-Silva D, Guadalupe C, Sam-Castañeda E.   +2 more
europepmc   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

Molecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski, Molly R. Danks, John P. Thomson, Morwenna Muir, Martin Lee, John C. Dawson, Ana T. Amaral, Juan Diaz‐Martin, David S. Moura, Javier Martin‐Broto, Ali Alsaadi, Donald M. Salter, Ailsa J. Oswald, Graeme Grimes, Larry Hayward, Ted R. Hupp, Karen Sisley, Paul H. Huang, Neil O. Carragher, Valerie G. Brunton   +19 more
wiley   +1 more source

Legal residency status and its relationship with health indicators among Syrian refugees in Lebanon: a nested cross-sectional study

Marie‐Elizabeth Ragi, Hala Ghattas, Berthe Abi Zeid, Hazar Shamas, Noura El Salibi, Sawsan Abdulrahim, Jocelyn DeJong, Stephen J. McCall, The Caep Study Group   +8 more
openalex   +1 more source