Results 291 to 300 of about 1,506,645 (358)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Rural-Urban Differences in the Prevalence and Correlates of Elder Mistreatment. [PDF]

open access: yesJ Appl Gerontol
Henning-Smith C   +5 more
europepmc   +1 more source

Quality Indicators for Drug Dispensing in Community Pharmacies: A Scoping Review Protocol. [PDF]

open access: yesJ Eval Clin Pract
Caxico-Vieira LJS   +6 more
europepmc   +1 more source

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