Results 321 to 330 of about 12,741,957 (410)

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Inequalities in care-seeking behaviour for childhood acute respiratory tract infection in Mauritania: evidence from the WHO health equity assessment toolkit of two national health surveys. [PDF]

BMJ Open
Tebeje TM, Eshun G.
europepmc   +1 more source

Society’s Attitude Toward Spousal Physical Abuse: Findings from the Philippines National Demographic and Health Survey, 2022

Wah Wah Myint, Roaa Aggad, Qiping Fan, Chimuanya Osuji, Heather Clark, E. Lisako J. McKyer   +5 more
openalex   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Increasing childhood illnesses (diarrhea and fever) and decreasing care-seeking practices in Nepal: Insights from three most recent Demographic and Health Surveys (2011, 2016 and 2022). [PDF]

PLOS Glob Public Health
Khatri RB, Dhital R, Tuladhar S, Mishra RK, Assefa Y.   +4 more
europepmc   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Reactions to Sexual, Substance Use, and Mental Health Surveys Among Rural Sexual Minority Men. [PDF]

Health Educ Behav
Montemayor BN, Owens C.
europepmc   +1 more source

Magnitudes of Informed choice of modern Contraceptive Methods among reproductive age women in Eastern Africa countries: A Multilevel Analysis of Demographic and Health Survey.

Gebreeyesus Abera Zeleke (19535761), Birtukan Atena Negash (21387746), Kassaw Belay Shiferaw (21387749), Berhan Tekeba (15353895), Tadesse Tarik Tamir (15338736), Workie Zemene Worku (16414613), Alebachew Ferede Zegeye (15338733)   +6 more
openalex   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source