Results 71 to 80 of about 29,242,323 (296)

Integrated Care in Epilepsy Management: A Scoping Review of the Models and Components of Health and Social Care Delivery

International Journal of Integrated Care
Introduction: Epilepsy is the most common neurological condition globally. Integrating health and social care is fundamental in epilepsy management, but the scope of progress in this area is unclear.
Samantha Spanos, Karen Hutchinson, Tayhla Ryder, Frances Rapport, Nicholas Goodwin, Yvonne Zurynski   +5 more
doaj   +1 more source

Interrogating resilience of health systems

, 2022
Introduction Health systems have experienced major shocks and will continue to encounter various forms of disruptions as observed in the increased frequency and intensity of catastrophic events such as extreme weather events, natural disasters, political conflicts and pandemics.
openaire   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Macro-health system governance and the UHC agenda : key learnings from the COVID-19 pandemic [PDF]

, 2021
This STG Resilience Paper is part of the Commission Research Report and Interim Progress Report (June 2021) published by Reform for Resilience.• Prior to the Covid-pandemic, the ‘Political Declaration of the High-Level Meeting on Universal Health ...
HUCKEL SCHNEIDER, Carmen
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Health resilience requires rigorous human rights assessment [PDF]

, 2021
This STG Resilience Paper is part of the Commission Research Report and Interim Progress Report (June 2021) published by Reform for Resilience.• Compliance with human rights is an important element of health resilience, generating popular legitimacy ...
SCHEININ, Martin
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Sustainability and resilience in the Spanish health system

, 2021
The Covid-19 pandemic has been the biggest stress test to the Spanish national health system (Sistema Nacional de Salud, SNS) since its inception in 1986.
López i Casasnovas, Guillem, Arasanz Goset, Àlex, López Seguí, Francesc, 1991-   +2 more
core  

Emergency medical services clinicians in the United States are increasingly exposed to death

Journal of the American College of Emergency Physicians Open, 2023
Introduction Exposure to patient death places healthcare workers at increased risk for burnout and traumatic stress, yet limited data exist exploring exposure to death among emergency medical services (EMS) clinicians.
Amelia Breyre, Remle P. Crowe, Antonio R. Fernandez, Alexandra Jabr, J. Brent Myers, Douglas F. Kupas   +5 more
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source