Results 191 to 200 of about 81,095,511 (308)

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Health care systems in transition: San Marino

, 2002
78 p.The Health Systems in Transition (HiT) series provide detailed descriptions of health systems in the countries of the WHO European Region as well as some additional OECD countries.
Busse, Reinhard, European Observatory on Health Systems and Policies, Cetani, Teresa, World Health Organization. Regional Office for Europe   +3 more
core  

"It cannot depend solely on the parents"-professionals' perspectives on patient journeys of children with chronic conditions across health and social care in Germany. [PDF]

Eur J Pediatr
Herr CJ, Herrler A, De Bock F.
europepmc   +1 more source

Public health systems and services research: an emerging field of research for CJPH to promote

Canadian Journal of Public Health, 2023
Neudorf, Cordell, McLaren, Lindsay, Laplante, Odette, Masuda, Jeff   +3 more
openaire   +2 more sources

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Enhancing integration for greater sustainability of HIV, TB and malaria responses: insights and lessons from African community-led monitoring programs. [PDF]

Front Public Health
Oberth G, Bozinovski J, Perez S.
europepmc   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Biobanking in Ireland: Moving Forward. Irish Health Research Forum Recommendations and Event Report [PDF]

This report presents the proceedings of the Irish Health Research Forum on November 16th 2023, focusing on progressing biobanking in Ireland, and makes key recommendations for moving biobanking forward.Roche Products ...
Health Research Charities Ireland
core  

Geo-Analytic Decision Support for Federal Behavioral Health Prioritization Among American Indian and Alaska Native Populations: Exploratory Study. [PDF]

JMIR Public Health Surveill
Paschane DM, Ontiveros M, Snyder JE.
europepmc   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source