Results 301 to 310 of about 3,759,449 (356)

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Avoidable pitfalls on the path to health financing self-reliance in low-income and middle-income countries. [PDF]

BMJ Glob Health
Barasa E, Chuma J, Nonvignon J, Adeyi OO.   +3 more
europepmc   +1 more source

Strengthening primary health care service competency: a scoping review of challenges, influencing factors, and enhancement strategies. [PDF]

Front Public Health
Yang S, Bai C, Zhao Y, Wang J, Jin H, Harris-Roxas B, Liu Y, Shen F, Zhao H, Ma L, Shi L, Yu D.   +11 more
europepmc   +1 more source

Personalised Psychological Care in Hospitals: An Organisational Model of Integrated, Patient- and Staff-Centred Services (2019-2024). [PDF]

J Pers Med
Chieffo DPR, Massaroni V, Delle Donne V, Lafuenti L, Monti L, Arcangeli V, Moriconi F, Ferrarese D, Galluzzi R, Mercuri EM, Sani G, Tortora G, Gasbarrini A.   +12 more
europepmc   +1 more source

Assessing the antimicrobial resistance testing capacity of public and private veterinary laboratories in Kenya. [PDF]

One Health Outlook
Morang'a AK, Muloi DM, Aanonsen H, Moodley A.   +3 more
europepmc   +1 more source

Public health round-up. [PDF]

Bull World Health Organ
europepmc   +1 more source

Medicare and Medicaid Behavioral Health Service Use Among Dual-Eligible Special Needs Plan Enrollees.

JAMA Netw Open
Kim H, Edelstein S, Senders A, Cheekati M, Lindner SR, McConnell KJ, Jung J.   +6 more
europepmc   +1 more source