Results 31 to 40 of about 711,638 (259)

Patient predictors of poor drug sensitive tuberculosis treatment outcomes in Kyiv Oblast, Ukraine [version 2; peer review: 2 approved, 1 approved with reservations]

open access: yesF1000Research, 2018
Background: Ukraine has high rates of poor treatment outcomes among drug sensitive tuberculosis (DSTB) patients, while global treatment success rates for DSTB remain high.
Omowunmi Aibana   +7 more
doaj   +1 more source

Commentary: Partnership for the Future of Public Health Services and Systems Research [PDF]

open access: yesHealth Services Research, 2009
For the Robert Wood Johnson Foundation, this edition of HSR is the end of the beginning for Public Health Services and Systems Research (PHSSR). HSR is the premier health services research journal in the nation, and to have top quality research on PHSSR published in this prestigious journal demonstrates that PHSSR is a bona fide research field that ...
Debra Joy, Pérez, Michelle Ann, Larkin
openaire   +2 more sources

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

Improving data transparency in clinical trials using blockchain smart contracts [version 1; referees: 3 approved]

open access: yesF1000Research, 2016
The scientific credibility of findings from clinical trials can be undermined by a range of problems including missing data, endpoint switching, data dredging, and selective publication. Together, these issues have contributed to systematically distorted
Timothy Nugent   +2 more
doaj   +1 more source

Health‐Related Social Needs in Children With Sickle Cell Disease Are Associated With Worse Health‐Related Quality of Life

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell disease (SCD) face multiple acute and chronic medical complications that may impact their quality of life as reported by patients themselves. Health‐related social needs (HRSNs), such as food and housing insecurity, are common in people with SCD, but the association between HRSNs and patient‐reported ...
Sarah J. Marks   +5 more
wiley   +1 more source

How blockchain-timestamped protocols could improve the trustworthiness of medical science [version 1; referees: 2 approved]

open access: yesF1000Research, 2016
Trust in scientific research is diminished by evidence that data are being manipulated. Outcome switching, data dredging and selective publication are some of the problems that undermine the integrity of published research.
Greg Irving, John Holden
doaj   +1 more source

Genomic Diversity and Clinical Variability in Pediatric Primary Cutaneous Anaplastic Large Cell Lymphoma: A Case Series

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger   +7 more
wiley   +1 more source

Towards a systems approach for chronic diseases, based on health state modeling [version 1; referees: 2 approved]

open access: yesF1000Research, 2017
Rising pressure from chronic diseases means that we need to learn how to deal with challenges at a different level, including the use of systems approaches that better connect across fragments, such as disciplines, stakeholders, institutions, and ...
Michael Rebhan
doaj   +1 more source

Central Nervous System Neuroblastoma, FOXR2‐Activated: A Pooled Analysis of Published Clinical Outcomes

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan   +1 more
wiley   +1 more source

How blockchain-timestamped protocols could improve the trustworthiness of medical science [version 3; referees: 3 approved]

open access: yesF1000Research, 2017
Trust in scientific research is diminished by evidence that data are being manipulated. Outcome switching, data dredging and selective publication are some of the problems that undermine the integrity of published research.
Greg Irving, John Holden
doaj   +1 more source

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