Results 61 to 70 of about 81,095,511 (308)

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

Blockchain protocols in clinical trials: Transparency and traceability of consent [version 5; referees: 1 approved, 2 approved with reservations, 2 not approved]

F1000Research, 2018
Clinical trial consent for protocols and their revisions should be transparent for patients and traceable for stakeholders. Our goal is to implement a process allowing for collection of patients’ informed consent, which is bound to protocol revisions ...
Mehdi Benchoufi, Raphael Porcher, Philippe Ravaud   +2 more
doaj   +1 more source

Health Systems Research, Health Services Research, and Population Health Research

Abstract In this book, we will give an overview of what is known about the relationships between the design and structure of health systems, health service provision and utilisation, and inequalities in population health. This will show the added value of combining health systems, health services, and population health research; areas
Peter P. Groenewegen, Ilmo Keskimäki, Alastair H. Leyland   +2 more
openaire   +1 more source

The Impact of the COVID‐19 Pandemic on Childhood Cancer Survival: A Population‐Based Assessment of Survival Patterns Between 2015 and 2023 in Germany

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann, Maike Wellbrock, Javier Louro, Arndt Borkhardt, Martin Schrappe, Claudia Trübenbach, Desiree Grabow, Cécile M. Ronckers, Joachim Schüz   +8 more
wiley   +1 more source

Mapping the Multidisciplinary Field of Public Health Services and Systems Research

American Journal of Preventive Medicine, 2011
Public health services and systems research (PHSSR) is the field of study charged with evaluating the public health system. PHSSR currently lacks a clear identity integrating the many theories, approaches, and disciplines contributing to the field.Experts in PHSSR were consulted to identify 11 key published PHSSR studies.
Jenine K, Harris, Kate E, Beatty, Jesse D, Lecy, Julianne M, Cyr, Robert M, Shapiro   +4 more
  +8 more sources

Point-of-contact Interactive Record Linkage (PIRL): A software tool to prospectively link demographic surveillance and health facility data [version 2; referees: 2 approved]

Gates Open Research, 2018
Linking a health and demographic surveillance system (HDSS) to data from a health facility that serves the HDSS population generates a research infrastructure for directly observed data on access to and utilization of health facility services.
Christopher T. Rentsch, Chodziwadziwa Whiteson Kabudula, Jason Catlett, David Beckles, Richard Machemba, Baltazar Mtenga, Nkosinathi Masilela, Denna Michael, Redempta Natalis, Mark Urassa, Jim Todd, Basia Zaba, Georges Reniers   +12 more
doaj   +1 more source

Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari, Regina Hadi Putri, Fatimah Assyifa, Judith Spijkerman, Gertjan Johannes Kaspers, Susi Susanah   +5 more
wiley   +1 more source

The effect of minimum volume standards in hospitals (MIVOS) — protocol of a systematic review

Systematic Reviews, 2023
Background The volume-outcome relationship, i.e., higher hospital volume results in better health outcomes, has been established for different surgical procedures as well as for certain nonsurgical medical interventions.
Julia Scharfe, Stefanie Pfisterer-Heise, Charlotte Mareike Kugler, Eni Shehu, Tobias Wolf, Tim Mathes, Dawid Pieper   +6 more
doaj   +1 more source

Economic burden of excess weight among older adults in Singapore: a cross-sectional study

BMJ Open, 2022
Objectives To estimate the incremental per capita and aggregate direct and indirect costs of excess weight among older adults (aged 40–80) in Singapore.Design Secondary data analysis of an existing cross-sectional surveySetting Residential districts in ...
Ecosse Lamoureux, Eric Andrew Finkelstein, Vinh Anh Huynh, Chay Junxing, Kwang Wei Tham   +4 more
doaj   +1 more source

Language, Culture, and Cancer: Qualitative Insights Into Communication Disparities Among Spanish‐Speaking Caregivers of Children With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Latino children are projected to make up nearly one‐third of United States (US) children by 2060, and many of their caregivers speak Spanish. Prior survey research has documented communication difficulties for Spanish‐speaking caregivers of children with cancer, but contemporary qualitative data are limited.
Jenny Ruiz, Alejandra Curbelo‐Paz, Sonia Morales, Elizabeth Contreras, Amy Houtrow, Scott H. Maurer, Judy C. Chang   +6 more
wiley   +1 more source