Results 121 to 130 of about 22,551,970 (267)
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
Modeling of the biomechanics of posture and balance
, 1988 Thesis (Ph. D.)--Massachusetts Institute of Technology, Division of Health Sciences and Technology, 1988.Title as it appeared in M.I.T. Graduate List, February 1988: Modeling the biomechanics of posture and balance.Bibliography: leaves 172-176.by Patrick
Riley, Patrick O. (Patrick Owen)
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Implementing an electronic medical record system: successes, failures, lessons
International Journal of Integrated Care, 2007 Anne Moen
doaj +3 more sources
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Surgical diagnostics, guidance, and intervention using optical coherence tomography
, 1998 Thesis (Ph.D.)--Harvard--Massachusetts Institute of Technology Division of Health Sciences and Technology, 1998.Includes bibliographical references (leaves 214-229).by Stephen Allen Boppart.Ph ...
Boppart, Stephen Allen
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Nuclear spin transfer studies of chemical reactions in living systems [PDF]
, 1987 Thesis (Ph. D.)--Massachusetts Institute of Technology, Harvard-MIT Division of Health Sciences and Technology Program in Medical Engineering and Medical Physics, 1987.Bibliography: leaves 212-227.by Eric W.
McFarland, Eric W. (Eric Wesley)
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Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Medical Devices: Evidence and Research, 2017 Sonal Batra,1 Ross A Baker,2 Tao Wang,3 Felicia Forma,4 Faith DiBiasi,3 Timothy Peters-Strickland5 1Department of Psychiatry, Rutgers Robert Wood Johnson Medical School, Piscataway, 2Global Medical Affairs, Otsuka Pharmaceutical Development and ...
Batra S +5 more
doaj
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source