Results 211 to 220 of about 13,430,401 (352)

Learning from success: the main drivers of the maternal and newborn health transition in seven positive-outlier countries and implications for future policies and programmes. [PDF]

BMJ Glob Health
Campbell OMR, Amouzou A, Blumenberg C, Boerma T, Countdown to 2030 Exemplars Collaboration.   +4 more
europepmc   +1 more source

How the epidemiological transition affects health policy isues in three Latin American countries [PDF]

The authors focus on health policy issues associated with health reform needed to meet the health needs arising from the demographic and epidemiological transitions.
Bobadilla, Jose Luis, de A. Possas, Cristina   +1 more
core  

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Exploring Challenges and Opportunities in Hospital Disaster Preparedness: A Qualitative Study on the Perspectives of Hospital Incident Command System Members

Risk Management and Healthcare Policy
Prinka Singh,1,2 Sujan Sapkota,3 Nebil Achour,4 Luca Ragazzoni,1,2 Hamdi Lamine1,5 1CRIMEDIM-Center for Research and Training in Disaster Medicine, Humanitarian Aid and Global Health, Università Del Piemonte Orientale, Novara, 28100, Italy; 2Department ...
Singh P, Sapkota S, Achour N, Ragazzoni L, Lamine H   +4 more
doaj  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Sexual health, transition-related risk behavior and need for health care among transgender sex workers. [PDF]

Int J Transgend, 2019
Van Schuylenbergh J, Motmans J, Defreyne J, Somers A, T'Sjoen G.   +4 more
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Development and Validation of the Hospital-to-Home-Health Transition Quality (H3TQ) Index: A Novel Measure to Engage Patients and Home Health Providers in Evaluating Hospital-to-Home Care Transition Quality: A Novel Measure to Engage Patients and Home Health Providers in Evaluating Hospital-to-Home Care Transition Quality. [PDF]

Qual Manag Health Care
Arbaje AI, Hsu YJ, Keita M, Greyson S, Wang J, Werner NE, Carl K, Hohl D, Jones K, Bowles KH, Chan KS, Marsteller JA, Gurses AP, Leff B.   +13 more
europepmc   +1 more source

Introducing a sector-wide pooled fund in a fragile context: mixed-methods evaluation of the health transition fund in Zimbabwe. [PDF]

BMJ Open, 2019
D'Aquino L, Pyone T, Nigussie A, Salama P, Gwinji G, van den Broek N.   +5 more
europepmc   +1 more source