Results 91 to 100 of about 10,030,185 (350)

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

The development of a measure of social care outcome for older people. Funded/commissioned by: Department of Health

, 2002
An essential element of identifying Best Value and monitoring cost-effective care is to be able to identify the outcomes of care. In the field of health services, use of utility-based health related quality of life measures has become widespread, indeed ...
Healey, Andrew T., Knapp, Martin R J., Netten, Ann, Ryan, Mandy, Skatun, Diane, Smith, Paul, Wykes, Til   +6 more
core  

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

EQ-5D™-derived utility values for different levels of migraine severity from a UK sample of migraineurs

Health and Quality of Life Outcomes, 2012
Background To estimate utility values for different levels of migraine pain severity from a United Kingdom (UK) sample of migraineurs. Methods One hundred and six migraineurs completed the EQ-5D to evaluate their health status for mild, moderate and ...
Stafford Megan R, Hareendran Asha, Ng-Mak Daisy S, Insinga Ralph P, Xu Ruifeng, Stull Donald E   +5 more
doaj   +1 more source

Utility of medicines information leaflets in hypertensive care in a setting with low health literacy: A cross-sectional study

Medicine Access @ Point of Care, 2020
Introduction: Higher levels of health literacy improve utilization of health information, medication adherence and outcomes. Few studies evaluate the utility of medicines information in hypertensive care in settings with low health literacy.
Mtungwazi Kudzinesta, Mwangana Mubita, Francis Kalemeera, Brian Godman, Ester Hango, Dan Kibuule   +5 more
doaj   +1 more source

The demand for health: differences between the native Dutch and immigrants in the Netherlands [PDF]

This paper estimates the demand for health by using a health capital model for different population groups (native Dutch, Surinamese/Antillean, Moroccan, and Turkish) in the Netherlands. Also the effect of overweight on health utility is investigated. We
Cornelisse-Vermaat, Judith R., Maassen van den Brink, Henriette   +1 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Real-world utilities and health-related quality-of-life data in hemophilia patients in France and the United Kingdom

Patient Preference and Adherence, 2019
Liz Carroll,1 Gary Benson,2 Jérémy Lambert,3 Khadra Benmedjahed,3 Marek Zak,4 Xin Ying Lee51Haemophilia Society, London, UK; 2Northern Ireland Haemophilia Comprehensive Care Centre and Thrombosis Unit, Belfast City Hospital, Belfast, UK ...
Carroll L, Benson G, Lambert J, Benmedjahed K, Zak M, Lee XY   +5 more
doaj  

Deploying projected utility to predict health behaviour in health economics: a quantitative study

Scientific Reports
Expected utility is increasingly deployed as a predictor of health behaviour within the broader domain of health economics and health sciences in general. However, research shows that this concept only explains limited variance in health behaviour.
Damien S. E. Broekharst, Sjaak Bloem, Edward A. G. Groenland, Patrick P. T. Jeurissen, Michel van Agthoven   +4 more
doaj   +1 more source

A review and meta analysis of health state utility values in breast cancer [PDF]

Background and purpose: Health-related quality of life is an important issue in the treatment of breast cancer, and health-state utilities are essential for cost-utility analysis.
Brazier, J., Peasgood, T., Ward, S.
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