Results 101 to 110 of about 10,030,185 (350)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Health Utility Book (HUB)–Cancer: Protocol for a Systematic Literature Review of Health State Utility Values in Cancer

open access: yesMDM Policy & Practice, 2019
Background. Treatment options in oncology are rapidly advancing, and public payer systems are increasingly under pressure to adopt new but expensive cancer treatments.
Michael James Zoratti   +9 more
doaj   +1 more source

Randomised controlled trial and economic evaluation of a chest pain observation unit compared with routine care [PDF]

open access: yes, 2004
Objectives To measure the effectiveness and cost effectiveness of providing care in a chest pain observation unit compared with routine care for patients with acute, undifferentiated chest pain.
Angelini, K.   +11 more
core   +2 more sources

A structured review of health utility measures and elicitation in advanced/metastatic breast cancer

open access: yesClinicoEconomics and Outcomes Research, 2016
Background Health utilities are increasingly incorporated in health economic evaluations. Different elicitation methods, direct and indirect, have been established in the past.
Y. Hao, V. Wolfram, J. Cook
semanticscholar   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Health utility indices and equity considerations [PDF]

open access: yesJournal of Health Economics, 1997
The aim of this paper is to propose methods that incorporate equity concerns into cost utility analysis. The focus of the paper is on QALYs, but the results apply to health utility indices in general. Two interpretations of QALYs are considered: QALYs as (von Neumann Morgenstern) utilities and QALYs as measures of health.
openaire   +5 more sources

A comparison of five multi attribute utility instruments [PDF]

open access: yes
This paper presents the results of the validation study carried out to evaluate the Assessment of Quality of Life (AQoL) Instrument for the measurement of health related quality of life and utility.
Graeme Hawthorne   +2 more
core   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Recommendations for Using Online Social Networking Technologies to Reduce Inaccurate Online Health Information [PDF]

open access: yes, 2011
This short report highlights patients' increasing use of the Internet and online social networking technologies to seek health information, and the consequences of gaining information from sites with biased or inaccurate health information. Reflecting on
Young, SD
core   +1 more source

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