Results 181 to 190 of about 7,559,735 (429)

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Health and Safety Issues of an Aging Workforce [PDF]

, 2019
[Excerpt] What do we mean by an “aging workforce”? As we live longer and healthier, older people continue to grow as a proportion of the working population. The number of workers of age 45 and older has doubled since 1950. Workers \u3e55 years of age are
Brown, Nellie J
core   +1 more source

Daily walking habits can mitigate age-related decline in static balance: a longitudinal study among aircraft assemblers

Scientific Reports
Improving physical balance among older workers is essential for preventing falls in workplace. We aimed to elucidate the age-related decline in one-leg standing time with eyes closed, an indicator of static balance, and mitigating influence of daily ...
Kazuhiko Watanabe, Shoko Iizuka, Tatsuya Kobayashi, Saki Tsushima, Sora Hirohashi, Tomohiro Yoshimi, Masayoshi Zaitsu   +6 more
doaj   +1 more source

Changes, challenges and choices for the primary health care workforce: looking to the future [PDF]

, 2001
Susan Jenkins‐Clarke, Roy Carr‐Hill
openalex   +1 more source

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source

2018 Dentist Re-Licensure Survey Instrument [PDF]

, 2018
This survey was administered between January 1st, 2018 - March 1st, 2018 to Dentists. This instrument is used for data collection in biennium re-licensure of Dental professionals in the State of ...
Bowen Center for Health Workforce Research and Policy
core  

Methods for health workforce projection model: systematic review and recommended good practice reporting guideline

Human Resources for Health
Background Health workforce projection models are integral components of a robust healthcare system. This research aims to review recent advancements in methodology and approaches for health workforce projection models and proposes a set of good practice
John Tayu Lee, Ian Crettenden, My Tran, Daniel Miller, Mark Cormack, Megan Cahill, Jinhu Li, Tomoko Sugiura, Fan Xiang   +8 more
doaj   +1 more source

The global oral health workforce [PDF]

The Lancet, 2021
Lobbezoo, Frank, Aarab, Ghizlane
openaire   +3 more sources

Data-Driven Approach to assess and identify gaps in healthcare set up in South Asia [PDF]

ICONIP 2024
Primary healthcare is a crucial strategy for achieving universal health coverage. South Asian countries are working to improve their primary healthcare system through their country specific policies designed in line with WHO health system framework using the six thematic pillars: Health Financing, Health Service delivery, Human Resource for Health ...
arxiv  

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source