Results 201 to 210 of about 7,559,735 (429)

Mapping Hsp104 interactions using cross‐linking mass spectrometry

open access: yesFEBS Open Bio, EarlyView.
This study examines how cross‐linking mass spectrometry can be utilized to analyze ATP‐induced conformational changes in Hsp104 and its interactions with substrates. We developed an analytical pipeline to distinguish between intra‐ and inter‐subunit contacts within the hexameric homo‐oligomer and discovered contacts between Hsp104 and a selected ...
Kinga Westphal   +3 more
wiley   +1 more source

Beyond the pandemic: the relationship between macroeconomic conditions and healthcare worker shortages in the United States

open access: yesBMC Health Services Research
Background While the COVID-19 pandemic undoubtedly catalyzed healthcare workforce challenges, alone it does not explain ongoing workforce shortages. This study examines how broader economic trends and industry competition may influence worker movement in
Kyla F. Woodward   +3 more
doaj   +1 more source

Introducing L2M3, A Multilingual Medical Large Language Model to Advance Health Equity in Low-Resource Regions [PDF]

open access: yesarXiv
Addressing the imminent shortfall of 10 million health workers by 2030, predominantly in Low- and Middle-Income Countries (LMICs), this paper introduces an innovative approach that harnesses the power of Large Language Models (LLMs) integrated with machine translation models.
arxiv  

Alkane biosynthesis gene expression and its increased production in recombinant cyanobacteria

open access: yesFEBS Open Bio, EarlyView.
The transcription and mRNA structures of the alkane biosynthesis genes ado/aar were analysed in the representative cyanobacteria PCC 6803 and SK1‐2‐1, which produce C17H36 and C15H32, respectively. PCC 6803 transconjugants carrying these genes showed a 1.8‐ to 2.3‐fold increase in C17H36 production.
Misato Nagao   +4 more
wiley   +1 more source

Implementing agile healthcare frame works in the context of low income countries: Proposed Framework and Review [PDF]

open access: yesarXiv
Agile healthcare frameworks, derived from methodologies in IT and manufacturing, offer transformative potential for low-income regions. This study explores Agile integration in resource-constrained environments, focusing on Ghana. Key benefits include adaptability, iterative planning, and stakeholder collaboration to address infrastructure gaps ...
arxiv  

Hydrophobicity causes anomalous migration of cystine/glutamate antiporter SLC7A11 in SDS‐PAGE with low acrylamide concentration

open access: yesFEBS Open Bio, EarlyView.
SLC7A11 frequently migrates faster in SDS‐PAGE. The present study found that the high hydrophobicity of SLC7A11 causes its anomalous migration in SDS‐PAGE with a low concentration of acrylamide gel. Replacing isoleucine with asparagine reduced hydrophobicity and restored its normal migration at 55 kDa, revealing the role of hydrophobicity and gel ...
Nsengiyumva Emmanuel   +13 more
wiley   +1 more source

2017 Optometrist Re-Licensure Survey Instrument [PDF]

open access: yes, 2018
This survey was administered between February 1st, 2018 - April 1st, 2018 to Optometrists. This instrument is used for data collection in biennium re-licensure of Optometrist professionals in the State of ...
Bowen Center For Health Workforce Research and Policy
core  

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