Objective We aimed to identify unique disease trajectories within rheumatoid arthritis‐associated interstitial lung disease (RA‐ILD) based on longitudinal forced vital capacity (FVC) values and their associated clinical outcomes. Methods We performed a cohort study of RA‐ILD within the Veterans Health Administration from 1999‐2021. RA‐ILD patients were
Bryant R. England+9 more
wiley +1 more source
Reforming Healthcare by Consent: Involving Those who Matter [PDF]
Alison Hill
openalex +1 more source
Resilience, perceived control, and intention to receive additional vaccines for COVID-19 among healthcare university students: Mediating role of knowledge of vaccine and infection-preventive behaviors. [PDF]
Kondo A+4 more
europepmc +1 more source
Chronic Opioids in Gout: A Matched Cohort Study from the Veteran's Health Administration
Objective Though used frequently to treat flare, risk of chronic opioid exposure in gout has not been well defined. In this study, we examined the hypothesis that people with gout are more likely than individuals without gout to be prescribed chronic opioids over time.
Lindsay N. Helget+7 more
wiley +1 more source
Immediate Mobilisation After Elective Colorectal Surgery-Patients' and Healthcare Professionals' Experiences: A Qualitative Study. [PDF]
Thörn RW+3 more
europepmc +1 more source
Activation of NF‐κB Signaling by Optogenetic Clustering of IKKα and β
This study presents an optogenetic approach for graded clustering of eGFP‐fused proteins using an eGFP‐specific nanobody and engineered Cryptochrome 2 variants. The method enables potent, reversible activation of NF‐κB signaling via endogenous pathways, as confirmed by RNA sequencing. This versatile system provides a spatially and temporally controlled
Alexandra Anna Maria Fischer+8 more
wiley +1 more source
The Complex Dynamics of Violence and Burnout in Healthcare: A Closer Look at Physicians and Nurses. [PDF]
Çakır O+4 more
europepmc +1 more source
Implementing comprehensive and decentralised health systems
David Sanders, Mickey Chopra
doaj +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio+11 more
wiley +1 more source