Results 31 to 40 of about 1,153,450 (316)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Respiratory Research, 2019 Background Evidence on the economic impact of chronic obstructive pulmonary disease (COPD) for third-party payers and society based on large real world datasets are still scarce.
Florian Kirsch +6 more
doaj +1 more source
The cost of a single concussion in American high school football: a retrospective cohort study
Concussion, 2020 Aim: The potential financial burden of American football-related concussions (FRC) is unknown. Our objective was to describe the healthcare costs associated with an FRC and determine factors associated with increased costs.
Aaron M Yengo-Kahn +9 more
doaj +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Breast Cancer: Value-Based Healthcare, Costs and Financing
Acta Médica Portuguesa, 2017 Introduction: Breast cancer is the second most common oncological disease worldwide. To analyse the new disease specific funding programme (breast cancer) implemented at the Francisco Gentil Portuguese Institute of Oncology, Lisbon Center (Instituto ...
Ana Harfouche +6 more
doaj +1 more source
Massachusetts Health Care Reform: Six Years Later [PDF]
, 2012 Examines Massachusetts' implementation of healthcare reform since 2006 and outcomes to date, including expansion of coverage, gains in access to care, ongoing issues with rising costs, and changes needed to comply with federal healthcare ...
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Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
In Pursuit of Affordable Health Care: On the Ground Lessons From Families in Massachusetts [PDF]
, 2009 Based on focus group discussions, compares the coverage and healthcare costs of families with employer-sponsored insurance and those without after the state's 2006 healthcare reform.
Barbara Lyons +2 more
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FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
The Effects of Health Reform on Small Businesses and Their Workers [PDF]
, 2011 Synthesizes research findings about how the 2010 healthcare reform will affect small business owners and employees, including savings in healthcare costs and premium contributions, coverage for workers and dependents, offer rates, and number of ...
Linda J. Blumberg +2 more
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