Corynoxine exerts potent broad‐spectrum anticancer activity by directly targeting NQO1. This interaction dissociates the oncogenic NQO1‐PTPA complex, releasing PTPA to robustly activate the tumor suppressor PP2A. Consequently, downstream Raf/MEK/ERK and PI3K/AKT signaling pathways are suppressed, downregulating c‐Myc and driving tumor regression ...
Guoqing Hou +6 more
wiley +1 more source
A Multi-Criteria Decision Support Framework for Prioritizing the Repair of Failed Medical Devices: A Hospital Case Study. [PDF]
Tarakçı E, Duranay R, Kaplan MR.
europepmc +1 more source
A Magnetic‐Driven Self‐Rotation‐Stabilized Miniature Swimming Robot
Inspired by the stable rotational descent of seeds in nature, this study designs a magnetic‐driven self‐rotation‐stabilized miniature swimming robot (MSMSR). Based on a resonance‐driven strategy, the robot exhibits high swimming performance, offering enhanced directional swimming and improved resistance to water flow disturbances compared to existing ...
Fujun Wang +4 more
wiley +1 more source
Intelligent Lung Support in the Intensive Care Unit (IntelliLung): study protocol for an international observational, prospective, multicentre study. [PDF]
Theilen R +27 more
europepmc +1 more source
Quality and Readability of Four AI Chatbots Answering Search-Derived Patient Questions About Primary Aldosteronism: A Cross-Sectional Comparative Study. [PDF]
Chen J +6 more
europepmc +1 more source
Experiences and Perceptions of Patient Watch, a Rural Telehealth Case Management Model, for Frequent Presenters to the Emergency Department: A Longitudinal Mixed Methods Study. [PDF]
Malakellis M +6 more
europepmc +1 more source
Therapeutic adherence and associated factors among high-risk patients with type 2 diabetes in primary healthcare: a cross-sectional study using real-world data from the Madrid Region. [PDF]
Martín Trujillo MC +3 more
europepmc +1 more source
Effectiveness Assessment of a Multi-Functional Neonatal Incubator in the NICU. [PDF]
Choi H, Jang W.
europepmc +1 more source
Effects of Nurse-Led Interventions on Quality of Life and Self-Care Among Patients With Heart Failure: A Systematic Review. [PDF]
Yusoff RM, Lee WL, Abidin IZ.
europepmc +1 more source

