Results 41 to 50 of about 233,659 (210)

Risk Reduction of Healthcare Workers’ Exposure to COVID-19 using Failure Mode and Effect Analysis

International Journal of Research and Review, 2021
Background: The exposure to COVID-19 by staff has a major impact on healthcare system. Objective: identify potential failures related to the exposure of HCWs to COVID-19, evaluate the potential causes and effects, and the actions to mitigate the risk of exposure.
Humberto Guanche Garcell, Farid Ahmad Sohail, Tania M Fernandez Hernandez   +2 more
openaire   +1 more source

Quinolones modulate ghrelin receptor signaling: potential for a novel small molecule scaffold in the treatment of cachexia [PDF]

, 2018
Cachexia is a metabolic wasting disorder characterized by progressive weight loss, muscle atrophy, fatigue, weakness, and appetite loss. Cachexia is associated with almost all major chronic illnesses including cancer, heart failure, obstructive ...
Cano, Rafael, Juan Rodríguez, Rocío, Kandil, Dalia, McGlacken, Gerard P., Pastor Cavada, Elena, Schellekens, Harriët, Shaban, Hamdy, Shanahan, Rachel, Torres-Fuentes, Cristina   +8 more
core   +3 more sources

Health impact (HI-FMEA) decision support application for hospital health technology management [PDF]

International Journal of Research in Industrial Engineering
The research aims to create an innovative Healthcare Impact Failure Mode and Effects Analysis (Hi-FMEA) framework approach that integrates patient safety in identifying and prioritizing critical failure modes in medical equipment and derive appropriate ...
David Mutia, Peter Muchiri, Michael Munywoki, James Wakiru   +3 more
doaj   +1 more source

Failure Mode and Effects Analysis (FMEA) to prevent and contrast violence on Healthcare Workers (HWs) [PDF]

European Journal of Public Health, 2018
Issue: Violence on HWs is increasing in Italy. In our Trust violence-related working days lost(WDL) and Incident Reports (IR)raised from 134 and 19 in years2015-16 to 342 and16 in 1st semester2017.For this reason,the Risk Management Unit (RMU) launched a FMEA,a proactive tool to identify and reduce risks.
D Celotto, G Perri, F Farneti, D Fantini, S Degan, L Grillone, F Bellomo, D De Corti, M d'Angelo, C Battistella, S Brusaferro   +10 more
openaire   +2 more sources

Failure mode and effects analysis applied to central venous catheter placement

BMJ Open Quality
Despite diligent efforts, complications continue to occur during the placement of central venous catheters (CVCs). Healthcare Failure Mode and Effect Analysis has been promoted as a process improvement tool and this review describes the strategic ...
Daniel Harwood, Bruno Maranhao, James R Duncan, Ellen Wertenberger, Jacob Grant, Mona Ostman   +5 more
doaj   +1 more source

System hazards in managing laboratory test requests and results in primary care: medical protection database analysis and conceptual model [PDF]

, 2015
Objectives To analyse a medical protection organisation's database to identify hazards related to general practice systems for ordering laboratory tests, managing test results and communicating test result outcomes to patients.
Bowie, Paul, Dinwoodie, Mark, Hepworth, Neil, McKay, John, Price, Julie   +4 more
core   +1 more source

DEveloping a Complex Intervention for DEteriorating Patients using Theoretical Modelling (DECIDE study): study protocol [PDF]

, 2019
AIM: To develop a theory-based complex intervention (targeting nursing staff), to enhance enablers and overcome barriers to enacting expected behaviour when monitoring patients and responding to abnormal vital signs that signal deterioration. DESIGN:
Craig P., Davis R., French S., Johnston M., Lyons P. G., Martins A., McMillan S. S.   +6 more
core   +2 more sources

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

mHealth: providing a mindfulness app for women with chronic pelvic pain in gynaecology outpatient clinics: qualitative data analysis of user experience and lessons learnt [PDF]

, 2020
OBJECTIVES: To determine whether a pre-existing smartphone app to teach mindfulness meditation is acceptable to women with chronic pelvic pain (CPP) and can be integrated into clinical practice within the National Health Service (NHS) CPP pathways, and ...
Ball, E., Birch, J., Cantalapiedra Calvete, C., Dodds, J., Newton, S., Rivas, C., Rohricht, F., Steed, L., Taylor, S.   +8 more
core   +3 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source