Results 81 to 90 of about 1,520,376 (278)

Who pays for healthcare in Bangladesh? An analysis of progressivity in health systems financing

International Journal for Equity in Health, 2017
Background The relationship between payments towards healthcare and ability to pay is a measure of financial fairness. Analysis of progressivity is important from an equity perspective as well as for macroeconomic and political analysis of healthcare ...
Azaher Ali Molla, Chunhuei Chi
doaj   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Sustainability of healthcare financing in the Western Balkans : an overview of progress and challenges [PDF]

This paper explores the major challenges to the sustainability of health sector financing in the countries of the Western Balkans - Albania, Bosnia and Herzegovina, the Former Yugoslav Republic of Macedonia, Montenegro, Serbia and the province of Kosovo.
Bredenkamp, Caryn, Gragnolati, Michele
core  

Getting creative in healthcare: the contribution of creative activities to Australian healthcare [PDF]

, 2008
Executive summary Creative skills are widely distributed across economies, but their contributions to economic performance and social outcomes and their role in enabling nations and institutions to respond to competitive and other pressures are not ...
Stuart Cunningham, Janet Pagan, Pagan, Janet D., Cunningham, Stuart D., Peter Higgs, Higgs, Peter L.   +5 more
core   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Distress financing on inpatient health expenditure across States in India

BMC Health Services Research
Background Out-of-pocket (OOP) healthcare expenditures remain a significant burden and are a leading cause of distress financing, particularly among socioeconomically disadvantaged households in India.
Kamlesh Meena, Sanatan Nayak
doaj   +1 more source

Trends over time in enrollment in non-group health insurance plans by tobacco use in the United States

Preventive Medicine Reports, 2017
Healthcare.gov was created to facilitate the market for non-group insurance in states that did not establish their own marketplaces. In Healthcare.gov, families are asked to report their tobacco use status, and tobacco use surcharges of up to 50% may ...
Michael F. Pesko, Johanna Catherine Maclean, Cameron M. Kaplan, Steven C. Hill   +3 more
doaj   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Fairness in healthcare financing and catastrophic expenditure in India

Discover Public Health
Achieving equity in healthcare financing remains a major policy challenge in developing economies where households rely heavily on out-of-pocket (OOP) payments to access healthcare services.
Piya Ghosh, Jayanta Sen
doaj   +1 more source