Results 61 to 70 of about 1,520,376 (278)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Examining Tertiary Healthcare Quality Under Asset Leasing, Performance‐Based Financing, and Social Impact Bonds: The Role of Government Stewardship in a Cross‐Sectional Quantitative Study in Kenya

Health Science Reports
Background and Aims Tertiary healthcare systems in low‐ and middle‐income countries persistently suffer quality gaps due to inefficient financing and governance.
Ezekiel Karino, James Ndegwa, Vincent Were   +2 more
doaj   +1 more source

Domestic Resource Mobilisation for Sustainable Healthcare Financing in Nigeria: A Review

Nigerian Postgraduate Medical Journal
Domestic resource mobilisation (DRM) is vital for achieving sustainable healthcare financing in Nigeria, where dependence on external funding and oil revenues has long hindered health sector progress.
Amina Idris Bello, Maryam Abimbola Jimoh, Abdul-Rasheed Olalekan Tijani, Hafsat Abolore Ameen   +3 more
doaj   +1 more source

Self-Rated Health Trajectories among Married Americans: Do Disparities Persist over 20 Years?

Journal of Aging Research, 2018
The purpose of this study is to understand self-rated health (SRH) trajectories by social location (race/ethnicity by gender by social class) among married individuals in the United States. We estimate multilevel models of SRH using six observations from
Terceira A. Berdahl, Julia McQuillan
doaj   +1 more source

Sources of health care financing in Poland and Germany

Prawo Budżetowe Państwa i Samorządu, 2018
This paper focuses on public sources of a healthcare financing in Poland and in Germany. These systems are based primarily on the health insurance contributions. In Poland and in Germany a healthcare is also financed from state budgets. Author identified
Paweł Lenio
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Analysis of the impact of public-private partnership on the development of the domestic medical industry

Вестник университета
The development of the social sphere in the country depends on the development of healthcare and medical industry, which serve as its basis, both at the municipal and regional levels, and show the level of its development.
I. R. Elistratov
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

The Distributional Impact of Healthcare Financing in Nigeria: A Case Study of Enugu State [PDF]

The deregulation of healthcare financing and supply in Nigeria has shifted the healthcare system towards competitive market ideals. Households' decision to utilize healthcare is identical with healthcare financing.
William Munpuibeyi Fonta, Hyacinth Ementa Ichoku   +1 more
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