Results 41 to 50 of about 43,830 (247)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

A mixed methods study examining the impact of primary health care financing transitions on facility functioning and service delivery in Kenya: a study protocol [version 1; peer review: 1 approved, 2 approved with reservations]

Wellcome Open Research
Background Kenya has experienced several health financing changes that have implications for financing primary healthcare (PHC). These include transitions from funding by two key donors (the World Bank and the Danish International Development Agency ...
Jacinta Nzinga, Anita Musiega, Rose Nabi Deborah Karimi Muthuri, Ethan Wong, Peter Mugo, Wangari Ng’ang’a, Caitlin Mazzilli, Gillian Turner, Brittany Hagedorn, Nirmala Ravishankar, Anne Musuva, Felix Munene Murira, Edwine Barasa, Benjamin Tsofa   +13 more
doaj   +1 more source

Preferences on Policy Options for Ensuring the Financial Sustainability of Healthcare Services in the Kingdom of Saudi Arabia

Risk Management and Healthcare Policy, 2023
Najwa Ali Huraysi,1,2 Waleed M Kattan,1 Mohamed A Alqurashi,1 Bodour Ayman Fadel,1 Mohammed Khaled Al-Hanawi1,3 1Department of Health Services and Hospital Administration, Faculty of Economics and Administration, King Abdulaziz University, Jeddah, Saudi ...
Huraysi NA, Kattan WM, Alqurashi MA, Fadel BA, Al-Hanawi MK   +4 more
doaj  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

From oil reliance to financial resilience: have economic sanctions made OPEC countries’ healthcare financing independent from oil?

Cogent Business & Management
The OPEC governments mainly financed their budgets by relying on oil production, similar to many other governments globally. However, the world’s ongoing economic development, changes in countries’ political relationships, and exchange of sanctions could
Salem Al Mustanyir
doaj   +1 more source

Hardship financing of healthcare among rural poor in Orissa, India

BMC Health Services Research, 2012
Background This study examines health-related "hardship financing" in order to get better insights on how poor households finance their out-of-pocket healthcare costs. We define hardship financing as having to borrow money with interest or to sell assets
Binnendijk Erika, Koren Ruth, Dror David M   +2 more
doaj   +1 more source

PUBLIC FINANCING OF HEALTHCARE SERVICES [PDF]

Financial Internet Quarterly
Healthcare in Poland is mainly financed by public sector entities, among them the National Health Fund (NFZ), state budget and local government budgets. The task of the National Health Fund, as the main payer in the system, is chiefly currently financing the services.
openaire   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Can performance-based financing improve efficiency of health centers in Ethiopia? A Malmquist Productivity Index analysis

BMC Health Services Research
Introduction The Ethiopian government has introduced several healthcare financing reforms intending to improve efficiency. Piloting implementation of performance-based financing is one of these actions.
Mideksa Adugna, Girmaye Dinsa, Nelisiwe Khuzwayo   +2 more
doaj   +1 more source

PROBLEMS OF FINANCIAL PROVISION OF HEALTHCARE IN UKRAINE UNDER MARTIAL LAW

Клінічна та профілактична медицина
Introduction. Achieving universal health coverage and financial protection of the population is one of the key objectives of the Sustainable Development Goals.
Mykhailo D. Diachuk, Dmytro D. Diachuk, Oleg L. Zyukov   +2 more
doaj   +1 more source