Results 51 to 60 of about 43,830 (247)

Accelerated Reforms in Healthcare Financing: The Need to Scale up Private Sector Participation in Nigeria [PDF]

International Journal of Health Policy and Management, 2014
The health sector, a foremost service sector in Nigeria, faces a number of challenges; primarily, the persistent under-funding of the health sector by the Nigerian government as evidence reveals low allocations to the health sector and poor health system
Ufuoma John Ejughemre
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Self-Rated Health Trajectories among Married Americans: Do Disparities Persist over 20 Years?

Journal of Aging Research, 2018
The purpose of this study is to understand self-rated health (SRH) trajectories by social location (race/ethnicity by gender by social class) among married individuals in the United States. We estimate multilevel models of SRH using six observations from
Terceira A. Berdahl, Julia McQuillan
doaj   +1 more source

Sources of health care financing in Poland and Germany

Prawo Budżetowe Państwa i Samorządu, 2018
This paper focuses on public sources of a healthcare financing in Poland and in Germany. These systems are based primarily on the health insurance contributions. In Poland and in Germany a healthcare is also financed from state budgets. Author identified
Paweł Lenio
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Examining Tertiary Healthcare Quality Under Asset Leasing, Performance‐Based Financing, and Social Impact Bonds: The Role of Government Stewardship in a Cross‐Sectional Quantitative Study in Kenya

Health Science Reports
Background and Aims Tertiary healthcare systems in low‐ and middle‐income countries persistently suffer quality gaps due to inefficient financing and governance.
Ezekiel Karino, James Ndegwa, Vincent Were   +2 more
doaj   +1 more source

Domestic Resource Mobilisation for Sustainable Healthcare Financing in Nigeria: A Review

Nigerian Postgraduate Medical Journal
Domestic resource mobilisation (DRM) is vital for achieving sustainable healthcare financing in Nigeria, where dependence on external funding and oil revenues has long hindered health sector progress.
Amina Idris Bello, Maryam Abimbola Jimoh, Abdul-Rasheed Olalekan Tijani, Hafsat Abolore Ameen   +3 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Analysis of the impact of public-private partnership on the development of the domestic medical industry

Вестник университета
The development of the social sphere in the country depends on the development of healthcare and medical industry, which serve as its basis, both at the municipal and regional levels, and show the level of its development.
I. R. Elistratov
doaj   +1 more source

Out-of-Pocket health expenditure and sources of financing for delivery, postpartum, and neonatal health in urban slums of Bhubaneswar, Odisha, India

Indian Journal of Public Health, 2017
Background: Out-of-pocket expenditure (OOPE) is an obstacle in the path of getting universal health coverage in India. Objective: This study aimed to explore the OOPE, sources of funding, and experience of catastrophic expenditure (CE) for healthcare ...
Kirti Sundar Sahu, Bhavna Bharati
doaj   +1 more source