Results 91 to 100 of about 1,591,356 (281)
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
International Journal for Equity in Health, 2017 Background Healthcare financing should be equitable. Fairness in financial contribution and protection against financial risk is based on the notion that every household should pay a fair share.
Xianjing Qin +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
St. Vincent's Healthcare Group annual review 2003 [PDF]
, 2004 St.
St. Vincent's Healthcare Group Ltd.
core
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Healthcare System Reform: Public Opinion on the Healthcare Issues and its Financing
, 2006 The reluctance to carry the burden of the costs of possible reforms prevails despite the Czech healthcare is perceived as very objectionable area. There is strong support to establish only one medical insurance office as well as giving priority to raise ...
Bayer, Ivo
core
Case Studies in Healthcare Financing of Healthy Homes Services [PDF]
, 2016 This report is part of a multiyear project to document and demystify the landscape and opportunities surrounding healthcare financing for healthy homes services.The findings described are the result of 34 interviews conducted with Medicaid agencies ...
Katie Horton +4 more
core +1 more source
, 2018 The Healthcare Finance course provides students with a foundational understanding of financial principles and their practical applications in the health services sector. It aims to equip learners with the skills and knowledge necessary to effectively manage financial resources within healthcare organizations.
openaire +2 more sources
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Progressivity and determinants of out-of-pocket health care financing in Zambia [PDF]
, 2010 Includes bibliographical references.The need for health care financing mechanisms that are progressive in Zambia cannot be over-emphasized. It is necessary that health care financing mechanisms are in such a way that they are related to ability to pay ...
Mwenge, Felix
core +1 more source