Results 51 to 60 of about 1,476,378 (238)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

From oil reliance to financial resilience: have economic sanctions made OPEC countries’ healthcare financing independent from oil?

open access: yesCogent Business & Management
The OPEC governments mainly financed their budgets by relying on oil production, similar to many other governments globally. However, the world’s ongoing economic development, changes in countries’ political relationships, and exchange of sanctions could
Salem Al Mustanyir
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Can performance-based financing improve efficiency of health centers in Ethiopia? A Malmquist Productivity Index analysis

open access: yesBMC Health Services Research
Introduction The Ethiopian government has introduced several healthcare financing reforms intending to improve efficiency. Piloting implementation of performance-based financing is one of these actions.
Mideksa Adugna   +2 more
doaj   +1 more source

PROBLEMS OF FINANCIAL PROVISION OF HEALTHCARE IN UKRAINE UNDER MARTIAL LAW

open access: yesКлінічна та профілактична медицина
Introduction. Achieving universal health coverage and financial protection of the population is one of the key objectives of the Sustainable Development Goals.
Mykhailo D. Diachuk   +2 more
doaj   +1 more source

Preferences on Policy Options for Ensuring the Financial Sustainability of Healthcare Services in the Kingdom of Saudi Arabia

open access: yesRisk Management and Healthcare Policy, 2023
Najwa Ali Huraysi,1,2 Waleed M Kattan,1 Mohamed A Alqurashi,1 Bodour Ayman Fadel,1 Mohammed Khaled Al-Hanawi1,3 1Department of Health Services and Hospital Administration, Faculty of Economics and Administration, King Abdulaziz University, Jeddah, Saudi ...
Huraysi NA   +4 more
doaj  

Hardship financing of healthcare among rural poor in Orissa, India

open access: yesBMC Health Services Research, 2012
Background This study examines health-related "hardship financing" in order to get better insights on how poor households finance their out-of-pocket healthcare costs. We define hardship financing as having to borrow money with interest or to sell assets
Binnendijk Erika   +2 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Lost in the Vaso‐Occlusion: A Patient's Abdominal Pain Returns With a Vengeance

open access: yes
Pediatric Blood &Cancer, EarlyView.
Dunia Hatabah   +5 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

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