Results 91 to 100 of about 627,738 (287)
Drug Management Reviews in District Drug Management Unit and General Hospital [PDF]
Drug is one of the essential elements in healthcare that should be effectively and efficiently managed. Following the decentralization in 2001 in Indonesia, drug management has changed in district drug management units and also in District General ...
Handayani, R. S. (Rini) +2 more
core
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
The Triple Aim Journey: Improving Population Health and Patients' Experience of Care, While Reducing Costs [PDF]
Provides an overview of the Institute for Healthcare Improvement's initiative designed to help improve population health, enhance patients' experience of care, and slow the growth of per capita costs.
Douglas McCarthy, Sarah Klein
core
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
OPTIMIZATION OF TREATMENT AND PROGNOSTIC APPROACHES TO BENIGN PROSTATIC HYPERPLASIA COMPLICATIONS
The problem of treatment for benign prostatic hyperplasia (BHP) remains highly relevant due to the high prevalence of this disease, its negative impact on the quality of life, and high risk of serious complications, such as acute urinary retention, acute
S. M. Pikalov +6 more
doaj
Aim. To assess the effectiveness of preventive, diagnostic and therapeutic work of the oncological service of Krasnodar Region, analyze the epidemiological features of morbidity, mortality, indicators reflecting the diagnosis (the proportion of early ...
S. V. Sharov +3 more
doaj +1 more source
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Case of acute drug-induced hepatitis after halothane anesthesia
The aim of publication. To present the case of severe acute drug-induced hepatitis after halothane anesthesia in relation to significance of allergies history preoperative inquiry and assessment of medical management of patients, using modern prognostic ...
I. Yu. Pirogova +8 more
doaj
OPERATIONS ON THE CAROTID ARTERIES FOR ACUTE PERIOD OF ISCHEMIC STROKE
Introduction. The study reviewed the experience of surgical treatment of 145 patients in Samara State Clinical Hospital (SSCH) №1 named after N.I. Pirogov, city of Samara, during the period 2013 - 2016, which had 146 reconstructive operations on carotid ...
Mikhail S. Mikhailov +7 more
doaj +1 more source

