Results 71 to 80 of about 627,738 (287)
How was it for you? Experiences of participatory design in the UK health service [PDF]
, 2013 Improving co-design methods implies that we need to understand those methods, paying attention to not only the effect of method choices on design outcomes, but also how methods affect the people involved in co-design.
Andy Dearden +21 more
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Primary Hemophagocytic Lymphohistiocytosis in a Newborn Child
Zdorovʹe Rebenka, 2014 The article presents the data of clinical observation of hemophagocytic lymphohistiocytosis in newborn child, complicated with spontaneous splenic rupture. Issues of diagnosis according to the recommendations of the International society for the study of
A.I. Kozhemyaka +7 more
doaj +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Health Performance Evaluation using preventable mortality criteria
Здоровье мегаполиса, 2022 The article presents the results of a study assessing the impact of healthcare on the life expectancy of the population of Moscow. The study is based on the concept of preventable mortality, which makes it possible to identify reserves for reducing ...
A. E. Ivanova +3 more
doaj
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Aktualʹnaâ Infektologiâ, 2014 Relevance. Ukraine is at one of the leading places in Eastern Europe on the prevalence of HIV/AIDS. The epidemic continues with the trend towards further growth in all regions of Ukraine, but spread across the country is unevenly.
L.R. Shostakovich-Koretskaya +5 more
doaj +1 more source
The “Principal Purpose” Driven Life: How Hospitals Should Apply ERISA’s Church Plan Exemption After Advocate v. Stapleton [PDF]
, 2020 The United States’ health care industry is filled with numerous protections for individuals and entities who have objections based on religious beliefs and moral convictions.
Brown, Virginia L.
core +1 more source
Assessing the readiness to implement lean in healthcare institutions – a case study [PDF]
, 2018 We develop a lean readiness framework and an assessment methodology to quantify the readiness of healthcare institutions for implementing lean. We use stakeholder theory and work with a lean implementation team responsible for process improvement in a ...
Gurumurthy, Anand +3 more
core +1 more source