Results 201 to 210 of about 1,759,168 (268)

Network based approach identifies miR‐145‐3p as a central regulatory hub associated to the progression from localized to metastatic medullary thyroid carcinoma

The Journal of Pathology, EarlyView.
Abstract Medullary thyroid carcinoma (MTC) is a neuroendocrine tumor originating from calcitonin producing C‐cells and accounts for 1–5% of thyroid cancers. Total thyroidectomy is curative in localized disease (N0), whereas lymph node metastases (N1) are associated with poorer prognosis.
Anna Citarella, Manuela Petti, Zein Mersini Besharat, Caterina Alfano, Elena Splendiani, Sofia Trocchianesi, Sara Cassandro, Martina Chiacchiarini, Claudia Sabato, Francesca Gianno, Tanja Milena Autilio, Martina Brunetti, Giuseppina Catanzaro, Antonella Verrienti, Rossella Elisei, Raffaele Ciampi, Cristina Romei, Maria Grazia Castagna, Silvia Cantara, Vincenzo Marotta, Luciano Pezzullo, Lorenzo Farina, Cosimo Durante, Agnese Po, Elisabetta Ferretti   +24 more
wiley   +1 more source

Molecular, spatial, and AI‐enabled technologies for predicting neoadjuvant therapy response in locally advanced rectal cancer

The Journal of Pathology, EarlyView.
Abstract Pretreatment prediction of neoadjuvant response remains an unresolved challenge in locally advanced rectal cancer, where management is moving towards risk‐adapted and response‐oriented treatment strategies. Prediction remains difficult because response reflects interacting tumour‐intrinsic, immune, stromal, and spatial processes that are ...
Gina F Boot, Cibele Masotti, Claudia Corrò, Cédric Schraepen, Hannah L Williams, Thomas A Wright, Fiza Ishaqwala, Colin W Steele, Gertjan Rasschaert, Maxime W Lafarge, Enric Domingo, Inti Zlobec, Rodrigo Oliva Perez, Campbell SD Roxburgh, Timothy S Maughan, Sabine Tejpar, Thibaud Koessler, Viktor H Koelzer   +17 more
wiley   +1 more source

Avoiding the cost of complacency: barriers and solutions to ending the HIV epidemic in Europe. [PDF]

Front Public Health
Radu P, Hayes H, Tunnicliffe E, Mott D, Hampson G.   +4 more
europepmc   +1 more source

Where in the Prenatal Screening Pathway do Ethnic and Socioeconomic Inequalities Occur? A UK Retrospective Cohort Study

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective To examine if and where ethnic and socioeconomic inequalities arise within the English NHS prenatal screening pathway by investigating associations between ethnicity, socioeconomic deprivation, screening test type, further testing uptake, and pregnancy outcomes.
Michelle Peter, Dagmar Tapon, Lyn S. Chitty, Melissa Hill   +3 more
wiley   +1 more source

Identifying symptom-based subgroups in Sjögren's disease: a latent class analysis of a patient co-designed survey. [PDF]

BMJ Open Ophthalmol
Tynan G, Collins D, Sheehy E, Lauder M, Lima Passos V, Ní Gabhann-Dromgoole J.   +5 more
europepmc   +1 more source

Failure points in the early autism identification pathway for children aged 0–5 years: Why screening is not diagnosis

Pediatric Investigation, EarlyView.
Early autism identification in children aged 0–5 years should be understood as a linked pathway from concern to action. Screening has value, but clinically meaningful identification depends on escalation of concern, referral conversion, timely assessment, and needs‐based support.
Ruslan Kurmashev, Mavile Karaieva
wiley   +1 more source

Public knowledge, beliefs and behaviours related to antimicrobial resistance and antibiotics: a systematic review of studies in high-income countries. [PDF]

JAC Antimicrob Resist
Shields C, Epton T, Berry E, Sahm LJ, Fleming A, Lambrou I, Feeney R, Sahar NU, Dobbs M, Kandulu CC, Melia E, Shorter GW.   +11 more
europepmc   +1 more source

Sustainable Healthy Diet Transitions: An Examination of Media Discourse Concerning Beef in the United Kingdom From 2018 to 2022

Sustainable Development, EarlyView.
ABSTRACT The role of diet in individual and planetary health is increasingly scrutinised as consumers are encouraged to make food choices that balance health and sustainability, particularly with beef. While prior research has considered reduction from the perspective of alternate product acceptance, the social context of beef is less understood. Media
Sean Tanner, Mary McCarthy, David Giles
wiley   +1 more source

Embedding Sustainability Commitments in the Strategic Plans of European Higher Education Institutions

Sustainable Development, EarlyView.
ABSTRACT This study analyses how European universities embed the Sustainable Development Goals (SDGs) into their strategic planning, proposing an integrative and multistakeholder measurement tool—Strategizer Scoring System (SDG‐3S). The research combines the Delphi method, content analysis of 198 strategic plans from universities in 33 European ...
Sandra Barrio Campo, Sara Urionabarrenetxea, Leire San‐Jose   +2 more
wiley   +1 more source

The Diagnostic Utility of Ultrasound in Myxofibrosarcoma: Insights From a Multimodal Imaging Case Study

Ultrasound International Open
Neil Limaye, Hannah Masraf, Henry Conchie, Adrian Lim   +3 more
doaj   +1 more source