Results 81 to 90 of about 441,931 (268)

Advancing Biotherapeutic Treatment of Ulcerative Colitis Using Lipid Mesophases: Formulation Design and Preclinical Validation

Advanced Science, EarlyView.
Lipid mesophases provide a versatile platform for colon‐targeted delivery of biotherapeutics, protecting them from degradation while enhancing mucoadhesion and enabling localized, controlled release to the inflamed mucosa after oral or rectal administration. In a DSS‐induced colitis model, this strategy reduced disease activity, inflammatory biomarkers,
Rafaela Gazzi, Tiziana Cremona, Reto Czekalla, Emily Campbell, Marlene Schwarzfischer, Doris Pöhlmann, Vanessa Dobernig, Gerhard Rogler, Michael Scharl, Alessandra Bergadano, Raffaele Mezzenga, Martin Kuentz, Paola Luciani, Simone Aleandri   +13 more
wiley   +1 more source

Morphological features of autoimmune gastritis

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2014
Aim of investigation. To estimate presence of classical morphological signs of autoimmune gastritis (AIH) in patients with high titer of antiparietal cells antibodies.Material and methods. Overall 15 patients (3 men and 12 women, 28 to 72 years old) have
Ye. A. Losik, L. S. Selivanova, M. Yu. Konkov, T. L. Lapina, A. S. Tertychnyi, V. T. Ivashkin   +5 more
doaj  

Chinese Expert Consensus on the Clinical Application of Finerenone in Geriatric Comorbidities

AGING MEDICINE, EarlyView.
Mineralocorticoid receptor (MR) overactivation drives inflammation, oxidative stress, and fibrosis in the heart, kidneys, and vasculature, leading to cardiorenal dysfunction. MR signaling promotes hypertrophy, remodeling, and injury through pathways like oxidative stress and inflammation, resulting in vascular stiffness and progressive organ damage ...
Xiaoming Wang, Cuntai Zhang
wiley   +1 more source

Liver fibrosis and markers of endothelial function at metabolic syndrome and early disorders of carbohydrate metabolism

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2014
Aim of investigation. Complex estimation of endothelial function at non-alcoholic fatty liver disease (NAFLD) in association with early disorders of carbohydrate metabolism, in relation to liver fibrosis severity.Material and methods. Overall 67 patients
L. V. Chesnokova, I. M. Petrov, Ye. A. Sidorova, I. A. Troshina, Yu. A. Petrova   +4 more
doaj  

Leveraging Barangay Health Workers to Strengthen Geriatric Care in an Aging Philippines

AGING MEDICINE, EarlyView.
Population aging in the Philippines requires innovative, community‐based approaches to strengthen geriatric care delivery. This article highlights the potential of Barangay Health Workers as frontline partners in promoting healthy aging through early detection, chronic disease monitoring, and coordinated referral services.
Darin Jan C. Tindowen
wiley   +1 more source

Chronotype and Peripheral Clock Genes: Association With Frailty and Insomnia in Mexican Older Adults

AGING MEDICINE, EarlyView.
Chronotype, insomnia, frailty, and peripheral clock gene expression were evaluated in community‐dwelling older adults. Extreme morning chronotype was associated with lower odds of insomnia, whereas women showed higher odds of insomnia. Pre‐frail and frail participants exhibited lower peripheral clock gene expression patterns than robust individuals ...
Citlally E. Ortiz‐Vázquez, Paola Garcia‐delaTorre, Sergio Sánchez‐García, Lorena Aguilar‐Arnal, Lucía Mendoza‐Viveros   +4 more
wiley   +1 more source

Determinants of Knowledge and Usage of Generative Artificial Intelligence in Agricultural Extension: Evidence From Tennessee Extension Personnel

Agribusiness, EarlyView.
ABSTRACT This paper examines the determinants of generative AI (GenAI) knowledge and usage among agricultural extension professionals. Drawing on survey data from agricultural extension personnel in Tennessee, we employ regression analyses and latent Dirichlet allocation (LDA) for topic modeling of open‐ended responses to study the knowledge and usage ...
Abdelaziz Lawani, Jason de Koff, James Muriuki, Anna‐Liisa Ihuhwa   +3 more
wiley   +1 more source

ROLE OF IMMUNOHISTOCHEMICAL ANALYSISIN EVALUATION OF PREGRAVID ENDOMETRIUM IN PATIENTS UNDERGOING IN-VITRO FERTILIZATION PROGRAM

Сеченовский вестник, 2017
Uterine disorders can considerably contribute to infertility. In order to overcome many different causes of female infertility a complex of diagnostic and therapeutic procedures was established.
V. A. Krutova, Ya. A. Kovalenko, L. M. Chuprinenko, A. A. Ordokova, O. V. Tarabanova   +4 more
doaj  

Workplace Harassment and Consideration of Leaving Surgical Practice: A Nationwide Survey by the Japanese Society of Gastroenterological Surgery

Annals of Gastroenterological Surgery, EarlyView.
In this nationwide survey of 1967 members of the Japanese Society of Gastroenterological Surgery, 66% reported experiencing workplace harassment, and 56% of those affected had considered leaving surgical practice. These findings highlight the need for sustained, society‐wide efforts to prevent harassment and foster respectful and psychologically safe ...
Keisuke Kurimoto, Tsutomu Fujii, Yoshihiro Shirai, Atsuro Fujinaga, Masayuki Fukumoto, Sonoko Ishida, Koya Hida, Chie Tanaka, Tsunekazu Mizushima, Sachiyo Nomura, Ken Shirabe   +10 more
wiley   +1 more source

Modern methods of studying of human gastro-intestinal microflora

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2014
The aim of review. To discuss modern concepts on the structure and functions of intestinal microflora and its possible effect on development of certain diseases, as well as the basic methods of diagnostics of disorders of its qualitative and quantitative
Ye. A. Poluektova, O. S. Lyashenko, O. S. Shifrin, A. A. Sheptulin, V. T. Ivashkin   +4 more
doaj