Results 111 to 120 of about 2,069,271 (259)
CAR‐Engineered Cell Therapies Beyond Cancer: Reprogramming Fibrosis and Immune‐Mediated Inflammation
Advanced Science, EarlyView.CAR‐engineered cell therapies are expanding beyond cancer toward immune resetting, pathological‐cell clearance, matrix remodeling, and microenvironmental reprogramming in autoimmune, inflammatory, and fibrotic diseases. This Review compares CAR‐T, CAR‐macrophage, and CAR‐NK platforms and proposes controllable spatiotemporal reprogramming to align ...
Peng Jun Xu +6 more
wiley +1 more source
Tumor Exposomics: A New Paradigm for Individualized Continuous Exposure Monitoring
Advanced Science, EarlyView.Tumor exposomics integrates continuous monitoring of environmental exposures, endogenous biological responses, and behavioral factors within a unified temporal framework. By combining multimodal sensing technologies with AI‐enabled causal modeling, this emerging paradigm reconstructs exposure‐damage trajectories and supports individualized dynamic risk
Kaicheng Shen +6 more
wiley +1 more source
Journal of Family Medicine and Primary Care, 2019 Background: Tobacco smoking is considered as the second main cause of increased mortality rate and one of the major preventable causes of cardiovascular and pulmonary diseases worldwide. Although the damages caused by smoking are known, the prevalence of
Madeeha Malik +3 more
doaj +1 more source
Advanced Science, EarlyView.The SPG‐MpECis electrochemical POCT platform developed in this study enables direct detection of biomarkers in complex biological samples such as serum and fingerstick blood, demonstrating high concordance with results from clinical reference methods and holding broad potential for at‐home testing applications.
Menghan Li +10 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT African swine fever (ASF), caused by African swine fever virus (ASFV), is a devastating viral disease in domestic pigs and wild boar. ASFV is a large DNA virus whose capsid assembly takes place within perinuclear viral factories (VFs). Accumulating evidence has demonstrated that reticulophagy confers antiviral activity against multiple RNA ...
Rui Luo +9 more
wiley +1 more source
The healthcare professional and the Bolam test [PDF]
British Dental Journal, 2000 This article will cover the history of the tort of negligence and how the judgement in the case of Donoghue v Stevenson enabled the courts to 'develop the law' to allow the concept of a 'duty of care' to develop which was extended to include healthcare professionals.
openaire +2 more sources
Background and objective: Hospital discharge of older patients is a critical and intricate process that poses substantial challenges for patient safety.
Kempen, Thomas +7 more
core +1 more source
Chinese Expert Consensus on the Clinical Application of Finerenone in Geriatric Comorbidities
AGING MEDICINE, EarlyView.Mineralocorticoid receptor (MR) overactivation drives inflammation, oxidative stress, and fibrosis in the heart, kidneys, and vasculature, leading to cardiorenal dysfunction. MR signaling promotes hypertrophy, remodeling, and injury through pathways like oxidative stress and inflammation, resulting in vascular stiffness and progressive organ damage ...
Xiaoming Wang, Cuntai Zhang
wiley +1 more source
, 2020 Objective: In Malaysia, sexual health issues among young people encompassing premarital sex, the incidence of STI including HIV/AIDS, unintended pregnancy, unsafe abortion and the practice of baby abandonment.
Fallon, Debbie +1 more
core
Agribusiness, EarlyView.ABSTRACT This paper examines the determinants of generative AI (GenAI) knowledge and usage among agricultural extension professionals. Drawing on survey data from agricultural extension personnel in Tennessee, we employ regression analyses and latent Dirichlet allocation (LDA) for topic modeling of open‐ended responses to study the knowledge and usage ...
Abdelaziz Lawani +3 more
wiley +1 more source