ABSTRACT Astrocyte reactivity critically shapes neuroinflammatory outcomes after ischemic stroke, yet the upstream regulators governing astrocyte state transitions remain incompletely defined. Here, we identify the immunoproteasome subunit low molecular weight protein 2 (LMP2) as an important modulator of astrocyte functional remodeling following ...
Yanguang Mao +7 more
wiley +1 more source
Associations Between Community Resilience, Healthcare Resources, and Cognitive Disability, Distress, and Depression in the U.S. [PDF]
Chen J +5 more
europepmc +1 more source
Utilization of Healthcare Resources by Vascular Anomaly Patients: An Assessment of Healthcare Burden by Lesion Complexity. [PDF]
Truong AY +7 more
europepmc +1 more source
Photonic‐Enabled Energy‐Efficient Transparent Neuromorphic Computing Devices: A Review
Transparent photonic neuromorphic computing devices merge optics and brain‐inspired computing to overcome von Neumann bottlenecks with ultrafast, low‐energy processing. By exploiting transparent oxides, 2D materials, phase‐change materials, and hybrid heterostructures, these platforms enable photonic synapses, memory, and logic for see‐through edge ...
Shuvaraj Ghosh +8 more
wiley +1 more source
Healthcare resources and differences in kidney disease-related mortality in Italy: a longitudinal study. [PDF]
d'Errico A +9 more
europepmc +1 more source
Reducing food waste in Irish hospitals results, guidance and tips from a 3-year programme
The Green Healthcare programme (GHCP) aims to improve resource efficiency and help prevent and reduce waste and emissions from healthcare facilities in Ireland.
Green Healthcare
core
Porcine deltacoronavirus (PDCoV) infection induces severe intestinal inflammation and acute diarrhea in piglets, yet the molecular mechanism remains incompletely understood. The M protein activates NLRP3 inflammasome through dual mechanisms: direct binding to the NLRP3 LRR domain and disruption of TRIM31‐mediated K48‐linked ubiquitination.
Jinhui Hou +11 more
wiley +1 more source
Post-COVID-19 condition patients' utilisation of healthcare resources after implementation of an integrated care unit. [PDF]
Vicente-Gómez JÁ +7 more
europepmc +1 more source
Retrospective Study of Healthcare Resources Developed for Patients by Interprofessional Teams. [PDF]
White R +6 more
europepmc +1 more source
LRRK2‐mutant induced pluripotent stem cells (iPSCs) were derived from a patient with Parkinson's disease (PD). Using CRISPR/Cas9–mediated gene editing, the pathogenic LRRK2 mutations were precisely corrected, and isogenic dopaminergic neural progenitor cells (DA‐NPCs) were subsequently generated.
Qing Yan +29 more
wiley +1 more source

