Results 101 to 110 of about 18,119,591 (200)

Development and pilot testing of a prostate cancer polygenic risk report

BMC Medical Genomics
Background Polygenic risk scores (PRS) are increasingly being incorporated into clinical care, yet optimal strategies for communicating PRS results to patients and clinicians remain undefined.
Julia N. Griffin, Morgan E. Danowski, Haley L. Gerety, Katherine Lafferty, Marla L. Clayman, Ashley A. Antwi, Mercedes G. Bertero, Charles A. Brunette, Chris Gillespie, Louise Guentert, Niall J. Lennon, Julian Martin, Lauren S. Patel, Jason L. Vassy   +13 more
doaj   +1 more source

A Comprehensive Review of Hidradenitis Suppurativa: From Pathogenesis to Clinical Insights & Novel Therapeutic Advancements

International Journal of Medical Students
Hidradenitis suppurativa is a chronic, inflammatory, recurrent, and debilitating follicular skin disease that profoundly impacts patients' quality of life. Recent evidence suggests that follicular occlusion is the primary initiating event.
Jeevan Rivera-Díaz, Sofía Laguna Rocafort, Ingrid M. Bonilla Mercado, Alejandra Figueroa Moreda, Jose Rabelo Cartagena   +4 more
doaj   +1 more source

Risk of Non‐Arteritic Anterior Ischemic Optic Neuropathy in Idiopathic Intracranial Hypertension Patients Treated with GLP‐1 Receptor Agonists

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) have demonstrated significant weight‐reducing effects and may offer benefits in idiopathic intracranial hypertension (IIH); however, recent concerns about the risk of non‐arteritic anterior ischemic optic neuropathy (NAION) have emerged.
Faisal A. Al‐Harbi, Mohanad A. Alkuwaiti, Yazeed B. Alaql, Ahmed K. Alsaif, Ahmed A. Alessa, Meshari Ayed Alharbi, Mohammed Alfalah, Saud A. Alnaaim, Sajjad M. AlHaddad, Ahmed Y. Azzam   +9 more
wiley   +1 more source

Neurovascular Contacts in the Pathophysiology of Neuralgic Amyotrophy: An Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuralgic amyotrophy (NA) is a prevalent, monophasic, multifocal immune‐mediated neuropathy. A distinctive characteristic of the disease is the occurrence of nerve or fascicle constrictions and torsions (NA‐associated focal nerve lesions, NAFL). The pathophysiology underlying this phenomenon remains to be fully elucidated.
Johannes Fabian Holle, Andreas Leha, Volker Limmroth, Wolfram Windisch, Maximilian Zimmermann   +4 more
wiley   +1 more source

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru, Akansha Chandrasekar, Kyla Blasingame, Jonathan Rosen, Jesse M. Levine, Karla Salazar, Madhuri Chilakapati, Rod Foroozan, Victoria Hardwick, Jonathan M. Yarimi, Nikita Shukla, Timothy E. Lotze, Kristen S. Fisher, Alexander J. Sandweiss   +13 more
wiley   +1 more source

User evaluations of IT in healthcare : a case study of perceived fit of a health management information system [PDF]

, 2010
Includes bibliographical references (p. 70-74).Mobile systems are increasingly growing in developing countries and have been a key interest for organisations looking to make scalable solutions for the developing world-context. For the HIV/AIDS healthcare
Mukudu, Alfred M
core   +1 more source

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig, Nadav Amir, Maya Schiller, Roni Loebenstein, Johnatan Nissan, Marina Boxer, Shany Guly Gofrit, Gal Goshen, Sándor Beniczky, Nicola Maggio   +9 more
wiley   +1 more source

Mechanically-adaptive, resveratrol-eluting neural probes for improved intracortical recording performance and stability

npj Flexible Electronics
Intracortical microelectrodes are used for recording activity from individual neurons, providing both a valuable neuroscience tool and an enabling medical technology for individuals with motor disabilities.
Natalie N. Mueller, Mali Ya Mungu Ocoko, Youjoung Kim, Kate Li, Kaela Gisser, Gabriele Glusauskas, Isabella Lugo, Peter Dernelle, Anna Clarissa Hermoso, Jaime Wang, Jonathan Duncan, Lindsey N. Druschel, Francine Graham, Jeffrey R. Capadona, Allison Hess-Dunning   +14 more
doaj   +1 more source

Provider Experience with Outpatient Parenteral Antimicrobial Therapy in Veterans Affairs Healthcare Systems: a qualitative study

Antimicrobial Stewardship & Healthcare Epidemiology
Background: Variability in outpatient parenteral antimicrobial therapy (OPAT) management and challenges to providing recommended OPAT care can compromise patient safety and care quality. Little is known about how OPAT is currently delivered by healthcare
Elizabeth Scruggs-Wodkowski, Lauren Gauntlett, Amanda Blok, Danielle Helminski, Nicholas Henry, Sara Keller, Ronald Kendall, Manon Nitta, Allison Ranusch, Molly Harrod, Sarah Krein   +10 more
doaj   +1 more source

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe, Keizo Sugaya, Kentaro Hayashi, Keiko Hino, Yasuhiro Nakata, Kota Bokuda, Toshio Shimizu, Kazushi Takahashi   +7 more
wiley   +1 more source