Results 41 to 50 of about 18,119,591 (200)

Study Design and Rationale for The Breathe Easier With Tadalafil Therapy for Exercise‐Related Dyspnea in COPD‐PH (BETTER COPD‐PH)

Pulmonary Circulation
Dyspnea, a debilitating symptom of COPD, worsens health‐related quality of life (HRQL), reduces daily physical activity, increases health care utilization, and is more closely associated with survival than airflow limitation. Thus, having treatments that
Elena DeSanti, Matthew Jankowich, Gaurav Choudhary, Alan Morrison, Zachary K. Stanley, Eric Garshick, Marilyn L. Moy, Mohleen Kang, Cherry Wongtrakool, Ruxana T. Sadikot, Edward C. Dempsey, Matthew Griffith, Duc M. Ha, Christopher H. Schmid, Ronald H. Goldstein, Sharon Rounds, the BETTER COPD‐PH Study Group   +16 more
doaj   +1 more source

Rationing in healthcare [PDF]

, 2015
Rationing healthcare in some form is inevitable, even in wealthy countries, because resources are scarce and demand for healthcare is always likely to exceed supply.
Martin, Elizabeth, Elizabeth Martin
core   +2 more sources

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Saint Raphael Healthcare System, 1998 Annual Report [PDF]

, 1998
https://elischolar.library.yale.edu/hospital_st_raphael_annual_reports/1069/thumbnail ...
Saint Raphael Healthcare System
core   +1 more source

Sharing perspectives on feedback: a combined resident-faculty workshop

BMC Medical Education, 2022
Background Feedback is essential to medical education. Although the need for effective feedback delivery is well known, more recent focus is on understanding and strengthening the faculty-trainee relationship within which the feedback process is carried ...
Bo Kim, Aishwarya Rajagopalan, Edward M. Tabasky, Sparsha S. Reddy, David R. Topor   +4 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Getting creative in healthcare: the contribution of creative activities to Australian healthcare [PDF]

, 2008
Executive summary Creative skills are widely distributed across economies, but their contributions to economic performance and social outcomes and their role in enabling nations and institutions to respond to competitive and other pressures are not ...
Stuart Cunningham, Janet Pagan, Pagan, Janet D., Cunningham, Stuart D., Peter Higgs, Higgs, Peter L.   +5 more
core   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Saint Raphael Healthcare System, 1996 Annual Report [PDF]

, 1996
https://elischolar.library.yale.edu/hospital_st_raphael_annual_reports/1067/thumbnail ...
Saint Raphael Healthcare System
core   +1 more source