Results 51 to 60 of about 388,212 (312)

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Reinfection rate in a cohort of healthcare workers over 2 years of the COVID-19 pandemic

Scientific Reports, 2023
In this large cohort of healthcare workers, we aimed to estimate the rate of reinfections by SARS-CoV-2 over 2 years of the COVID-19 pandemic. We investigated the proportion of reinfections among all the cases of SARS-CoV-2 infection from March 10, 2020 ...
Ana Rubia Guedes, Maura S. Oliveira, Bruno M. Tavares, Alessandra Luna-Muschi, Carolina dos Santos Lazari, Amanda C. Montal, Elizabeth de Faria, Fernando Liebhart Maia, Antonio dos Santos Barboza, Mariana Deckers Leme, Francis M. Tomazini, Silvia Figueiredo Costa, Anna S. Levin   +12 more
doaj   +1 more source

Preventing Hospital Acquired Infections Through a Workflow-Based Cyber-Physical System

, 2016
Hospital acquired infections (HAI) are infections acquired within the hospital from healthcare workers, patients or from the environment, but which have no connection to the initial reason for the patient's hospital admission.
Bocicor, Maria Iuliana, Molnar, Arthur-Jozsef, Taslitchi, Cristian   +2 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

“An increase in COVID-19 patients would be overwhelming”: A qualitative description of healthcare workers’ experiences during the first wave of COVID-19 (March 2020 to October 2020) at Malawi’s largest referral hospital. [version 1; peer review: 2 approved]

Wellcome Open Research, 2022
Background  COVID-19 is currently a global health threat. Healthcare workers are on the front-line of the COVID-19 outbreak response and therefore at heightened risk of infection.
Nicola Desmond, Blessings M Kapumba, Felix Limbani, Tamara Phiri, Henry Mzinganjira, Henry C Mwandumba, Ben Morton, Jamie Rylance   +7 more
doaj   +1 more source

Attitudes and intentions toward seeking professional psychological help among Chinese healthcare workers during the COVID-19 pandemic [PDF]

, 2023
Ruirui Huang, Xiaoyan Peng, Shuai Yu, Yumei Tian, Chuanying Gao   +4 more
openalex   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Funding Community Health Worker Programs and Services in Minnesota: Looking to the Future [PDF]

, 2006
This report is a supplement to the 2006 report "Advancing Community Health Worker Practice and Utilization: The Focus on Funding"
Catherine Dower, Edward O'Neil, Melissa Knox, Vanessa Lindler   +3 more
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Nepalese migrants in Japan: What is holding them back in getting access to healthcare? [PDF]

PLoS ONE, 2018
INTRODUCTION:Migrants are one of the most deprived and vulnerable groups who receive the least health services in the society. Only a few studies have been conducted on access to healthcare among migrants in Asia, despite hosting 75 million migrants.
Prakash Shakya, Masako Tanaka, Akira Shibanuma, Masamine Jimba   +3 more
doaj   +1 more source