Results 71 to 80 of about 363,853 (309)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Cost-consequence analysis of influenza vaccination among the staff of a large teaching hospital in Rome, Italy: A pilot study.

open access: yesPLoS ONE, 2019
Flu vaccination, as well as being effective to prevent seasonal influenza, decreases staff illness and absenteeism and reduces costs resulting from loss of productivity. Despite the effectiveness of flu vaccination, the seasonal coverage among healthcare
Vittoria Colamesta   +12 more
doaj   +1 more source

Tracking Report 2008 Hanesbrands, Indonesia 720033877G [PDF]

open access: yes, 2008
This document is part of a digital collection provided by the Martin P. Catherwood Library, ILR School, Cornell University, pertaining to the effects of globalization on the workplace worldwide.
Fair Labor Association
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Implementation of a COVID-19 surveillance programme for healthcare workers in a teaching hospital in an upper-middle-income country.

open access: yesPLoS ONE, 2021
IntroductionThe reporting of Coronavirus Disease 19 (COVID-19) mortality among healthcare workers highlights their vulnerability in managing the COVID-19 pandemic.
Kim Sui Wan   +25 more
doaj   +1 more source

Point of Care Technology for Underserved Populations [PDF]

open access: yes, 2017
Point of Care technology is an emerging healthcare field. This technology allows for rapid, inexpensive, on-site testing for otherwise lengthy and costly laboratory tests. Leading infectious diseases can be tested immediately in non-invasive ways similar
Maloney, Anna
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Sending Our Petitions to God : Nigerian Immigrant Healthcare Worker Settlement, Gender and the Role of Religious Networks [PDF]

open access: yes, 2017
This paper provides a brief overview of a study aimed at understanding the lived experiences of health care migrants from Nigeria now living in Canada and their individual perceptions regarding their migration experience. We report here on an interesting
Adekola, Sheri, Walton-Roberts, Margaret
core   +1 more source

Varicella vaccination for healthcare workers [PDF]

open access: yesBMJ, 2005
Is beneficial to patients and staff I n December 2003, the Oka vaccine to prevent chickenpox (varicella) was licensed in the United Kingdom for use in susceptible healthcare workers.1 One year later a survey of consultant virologists, who are members of the Clinical Virology Network and who between them provide virology services for 38 trusts located
openaire   +2 more sources

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Home - About - Disclaimer - Privacy