KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph +7 more
wiley +1 more source
Why healthy life expectancy estimates diverge: insights from survey-based, administrative, and model-based metrics across Japanese prefectures, 2001-2019: a comparative ecological study. [PDF]
Nomura S +9 more
europepmc +1 more source
An analysis of life expectancy and economic production using expectile frontier zones [PDF]
The wealth of a country is assumed to have a strong non-linear influence on the life expectancy of its inhabitants. We follow up on research by Preston and study the relationship with gross domestic product.
Sabine K. Schnabel, Paul Eilers
core
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow +12 more
wiley +1 more source
Getting better or worse? How trends in healthy life expectancy within working age are shaped by diverging trends among age groups. [PDF]
Tetzlaff J +5 more
europepmc +1 more source
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
Evaluating Health Financing Typologies Through Healthy Life Expectancy and Infant Mortality: Evidence from OECD Countries and Türkiye. [PDF]
Yılmaz S, Çelik Y.
europepmc +1 more source
Multi-country clustering-based forecasting of healthy life expectancy. [PDF]
Levantesi S +3 more
europepmc +1 more source

