Results 91 to 100 of about 906,493 (292)

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

Advanced Science, EarlyView.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin, Mengjie Zhang, Wenying Liu, Wenlong Shen, Debao Li, Hongming Miao, Fang Deng, Gang Zhang, Yi Tian, Yi Zhang, Zhihu Zhao, Bing Ni   +11 more
wiley   +1 more source

Association of sleep hygiene knowledge and physical activity with sleep quality in nursing and medical students: a cross-sectional study

Frontiers in Sports and Active Living
BackgroundSleep quality and physical activity are fundamental factors in the optimal functioning of the human organism and maintaining overall health. This study aimed to evaluate the relationship between knowledge of sleep hygiene and physical activity ...
Jacksaint Saintila, David Javier-Aliaga, Norma del Carmen Gálvez-Díaz, Luz Antonia Barreto-Espinoza, Noemi A. Buenaño-Cervera, Yaquelin E. Calizaya-Milla   +5 more
doaj   +1 more source

Paving the Way to Elucidate Hg's Role in Tumorigenesis

Advanced Science, EarlyView.
Tumorigenesis can result from diverse environmental carcinogens. Among them, mercury—a lifelong bioaccumulative Group 2B carcinogen—has tumorigenic potential that remains poorly understood due to confounding co‐exposures and limited organ‐specific data.
Shouying Li, Rong Zhong, Zhenyang Yu, Hualing Fu, Jin Chen, Jia Wei, Ningwei Zhao, Le Qu, Tiantian Li, Wenli Tang, Huan Zhong   +10 more
wiley   +1 more source

Rapid Remodeling of the Human Gut Microbiome in Response to Short‐Term Animal Product Restriction and Associations with Host Molecular Phenotypes

Advanced Science, EarlyView.
A real‐world model of structured animal product restriction practiced for religious reasons reveals the dynamic adaptability of the human gut microbiome to dietary change and uncovers reductions in diversity and rare taxa loss. Integrated microbiome, metabolomic, and proteomic analyses uncover coordinated taxonomic and molecular shifts and identify ...
Christina Emmanouil, Maria Anezaki, Alexandros Simistiras, Stavros Glentis, Nikolaos Scarmeas, Pantelis Hatzis, Konstantinos Rouskas, Antigone S. Dimas   +7 more
wiley   +1 more source

Necessity of Rethinking about the Preventive Strategies of Addiction

International Journal of Community Based Nursing and Midwifery, 2017
According to the last official statistics of national organization, there are nearly 220 million addicted people in the world until 2008. Therefore, it seems that addiction has become a scourge of the world which cannot be dealt with by countries alone ...
Ali Riasaty
doaj  

Effects of Eat Better, Move More (EBMM) Educational Program on Obesity Rates in Latino Children Residing in Northwest Arkansas [PDF]

, 2019
Background: Childhood obesity, especially in ethnic minority populations, is a growing problem with no signs of improvement over the past decade. The Latino population is one of the fastest growing minority groups in the United States.
Jones, Allison
core   +2 more sources

Alternating High‐Fat and Polysaccharide Diets Modulates Gut Phage‐Bacterial Interplay

Advanced Science, EarlyView.
This study reveals how alternating high‐fat and polysaccharide diets reshape the human gut virome and enhance phage‐bacteria interactions. Using large‐scale metagenomic meta‐analysis and a time‐resolved mouse model, the authors show that diets strongly modulate phage abundance, lifestyle, and gene exchange, offering new insights into nutrition‐guided ...
Fengxiang Zhao, Ruiqi Zhang, Rujun Wei, Huimin Fan, Yongfei Hu, Wenyu Shi, Jinfeng Wang   +6 more
wiley   +1 more source

Physical activity and health behaviors of children from 4-6 classes of primary school living in the villages of the Lublin and Lodz voivodeships.

Journal of Education, Health and Sport, 2018
Introduction Health behaviors shape throughout life. The family is the first educational environment of the child, in which health habits are created. Nutrition and nutritional status in childhood and early adolescence determine the health of an adult ...
Paula Jankowska, Ewa Rudnicka-Drożak
doaj   +1 more source

Research and model of actual problems of psychological culture healthy lifestyle in the educational process [PDF]

, 2011
Стаття присвячена аналізу результатів психодіагностичного дослідження актуальних проблем психології становлення здорового способу життя в навчально-виховному процесі, описано модель і психологічні компоненти культури здорового способу життя.The article ...
Волошко, Наталія Іванівна
core  

Mapping Genetic Regulation of Transcription to Identify Functional Variants and Genes Associated with Pancreatic Cancer Risk

Advanced Science, EarlyView.
Integration of a pancreatic eQTL map with a GWAS meta‐analysis identifies 82 putative functional variants and 15 genes. The association between rs11102484 and pancreatic cancer risk is observed in a total of 5699 cases and 8467 controls. The G allele of rs11102484 weakens ZNF263 binding and the silencer‐promoter interaction, thereby increasing ST7L ...
Xiaoyang Wang, Hui Geng, Zhengyan Yao, Yuan Jiang, Can Chen, Zequn Lu, Shuangshuang Tian, Ming Zhang, Ruiyan Liu, Chenxi Feng, Bin Li, Xiaoping Miao, Jianbo Tian, Shaokai Zhang, Ying Zhu   +14 more
wiley   +1 more source