Results 161 to 170 of about 2,337,722 (307)

Healthy Lifestyle of Czech University Students

open access: yes, 2013
The thesis deals with the healthy lifestyle of Czech university students. The main objectives are to map the healthy lifestyle of Czech university students, especially to find out whether they follow the principles of healthy lifestyle, to find out their
Marholdová, Lucie
core  

Mitochondrial Quality Control in Degenerative Musculoskeletal Diseases: Signaling Networks and Therapeutic Landscapes

open access: yesAdvanced Science, EarlyView.
Mitochondrial quality control (MQC) collapse redefines osteoarthritis, intervertebral disc degeneration, and osteoporosis as disorders of organelle dysfunction. Damaged mitochondria leak mtDNA and metabolites, driving cGAS‐STING inflammation, epigenetic reprogramming, and metabolic memory.
Haiyang Gao   +7 more
wiley   +1 more source

Confirmatory factor analysis for healthy lifestyle habits.

open access: yes
Confirmatory factor analysis for healthy lifestyle habits.
Petra Bester (4174627)   +5 more
core   +1 more source

Hepatocyte CBX2 Safeguards Hepatic Lipid Homeostasis by Elevating Ca2+‐CaMKK2‐AMPK Signaling to Counter MASLD

open access: yesAdvanced Science, EarlyView.
In hepatocytes, CBX2 promotes H3K4me3 enrichment at the Orai1 promoter to enhance Orai1 transcriptional activation, thereby increasing intracellular Ca2+ levels. The elevated Ca2+ activates the CaMKK2‐AMPK signaling cascade, resulting in ACC phosphorylation and downstream metabolic regulation. This cascade suppresses de novo lipogenesis (Fasn, Acc, Scd‐
Xiang Wei   +18 more
wiley   +1 more source

Motivational Interviewing to Promote Healthy Lifestyle Behaviors: Evidence, Implementation, and Digital Applications [PDF]

open access: yes
Ahmed A Bahri Department of Family and Community Medicine, Jazan University, Jazan, Saudi ArabiaCorrespondence: Ahmed A Bahri, Email dr.bahri2010@gmail.comBackground: Chronic lifestyle-related diseases, including poor diet, physical inactivity, and ...
Bahri AA
core  

Noninvasive Detection and Subtyping of Esophageal Cancer by Circulating Cell‐Free mtDNA Fragmentomics: A Multi‐Center Validation Study

open access: yesAdvanced Science, EarlyView.
Circulating cell‐free mitochondrial DNA provides a robust, noninvasive platform for early detection and histological subtyping of esophageal cancer. This large multi‐center study validates consistently high accuracy across ethnically and geographically diverse cohorts, demonstrating strong potential to transform clinical management. ABSTRACT Esophageal
Yue Liu   +15 more
wiley   +1 more source

PHGDH‐Mediated Serine Metabolism in Nucleus Pulposus Cells Is a Potential Therapeutic Target for Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
When nucleus pulposus cells senesce, PHGDH decreases, reducing serine synthesis and glutathione, impairing antioxidant capacity. The intermediate α‐KG also drops, lowering JMJD3 demethylase activity, increasing H3K27me3 at the Rap1b promoter, and reducing Rap1b expression, whose down‐regulation in turn activates mTORC1 and suppresses autophagy ...
Hao‐Wei Xu   +5 more
wiley   +1 more source

The correlates of social capital and adherence to healthy lifestyle in patients with coronary heart disease

open access: yes, 2017
Jialie Fang,1,* Ji-Wei Wang,2,* Jiang Li,3 Hua Li,4 Chunhai Shao5 1Shanghai Jing’an District Center for Disease Control and Prevention, Shanghai, People’s Republic of China; 2Key Lab of Health Technology Assessment of Ministry of ...
Li H, Fang J, Li J, Wang JW, Shao C
core  

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