Results 91 to 100 of about 252,967 (293)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Home Medication Review among Patients with Chronic Diseases in Rural Villages of Pahang, Malaysia: A Case Report

open access: yesJournal of Pharmacy
Introduction: Home Medication Review (HMR) is crucial for optimising medication use and improving patient’s outcomes. Despite its potential benefits, HMR implementation in rural areas faces challenges.
Norny Syafinaz Ab Rahman   +2 more
doaj  

The Relationship of Clean and Healthy Living Behavior and the Incidence of Malaria: Systematic Review

open access: yesJurnal Ilmiah Kesehatan
Malaria is a tropical disease caused by the bite of the Anopheles mosquito. Malaria is an infectious disease that is of global concern. This disease still often causes extraordinary events.
Rusni   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Informing healthy building design with biophilic urbanism design principles: A review and synthesis of current knowledge and research [PDF]

open access: yes, 2012
Links between human health and wellbeing, and contact with nature are well understood in the fields of health and psychology, and more recently are gaining attention in the built environment industry. In 1984, E.O.
Reeve, Angela   +4 more
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Towards Healthy and Sustainable Human Settlement: The Ecological and Cultural Connation of Landsenses

open access: yesLand
The construction of a healthy and sustainable living environment requires a systematic integration of multidimensional elements such as the environment, society, and economy [...]
Jiang Liu, Yuhan Shao, Xinchen Hong
doaj   +1 more source

The Role of Government To Build Eco Community

open access: yesE3S Web of Conferences, 2018
As stated in Article 28 H Consitution on Republic of Indonesia 1945, that every person has rights of good and healthy environment, medical service. The needs of healthy environment in neighborhood is highly demand in a few years. People starts to realize
Putrijanti Aju
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Can food vouchers improve nutrition and reduce health inequalities in low-income mothers and young children:a multi-method evaluation of the experiences of beneficiaries and practitioners of the Healthy Start programme in England [PDF]

open access: yes, 2014
Background: Good nutrition is important during pregnancy, breastfeeding and early life to optimise the health of women and children. It is difficult for low-income families to prioritise spending on healthy food.
Green, Josephine M.   +24 more
core   +1 more source

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