Results 91 to 100 of about 9,073,327 (280)
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Introduction: Home Medication Review (HMR) is crucial for optimising medication use and improving patient’s outcomes. Despite its potential benefits, HMR implementation in rural areas faces challenges.
Norny Syafinaz Ab Rahman +2 more
doaj
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The purposes of the research are to analyzing, evaluating, and measuring the correlation between employee's perception of Germas (healthy life movement) on the behaviour of healthy living in the work environment, according to the recommendations in ...
Regina Nova Indradewi +2 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Malaria is a tropical disease caused by the bite of the Anopheles mosquito. Malaria is an infectious disease that is of global concern. This disease still often causes extraordinary events.
Rusni +3 more
doaj +1 more source
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Investigating satiety for healthy weight : Appetite control
Modulating feelings of hunger and satiety could be a promising approach in weight management. TNO Food & Nutrition offers advanced assessment tools to support the development of food products that help address issues of overweight and underweight.
Burgering, M.J.M.
core
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
The construction of a healthy and sustainable living environment requires a systematic integration of multidimensional elements such as the environment, society, and economy [...]
Jiang Liu, Yuhan Shao, Xinchen Hong
doaj +1 more source

