Results 91 to 100 of about 9,073,327 (280)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Home Medication Review among Patients with Chronic Diseases in Rural Villages of Pahang, Malaysia: A Case Report

open access: yesJournal of Pharmacy
Introduction: Home Medication Review (HMR) is crucial for optimising medication use and improving patient’s outcomes. Despite its potential benefits, HMR implementation in rural areas faces challenges.
Norny Syafinaz Ab Rahman   +2 more
doaj  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Pengaruh Persepsi Pegawai Akan Program Germas Terhadap Perilaku Hidup Sehat di Lingkungan Kerja Badan Narkotika Nasional

open access: yesMatrik, 2019
The purposes of the research are to analyzing, evaluating, and measuring the correlation between employee's perception of Germas (healthy life movement) on the behaviour of healthy living in the work environment, according to the recommendations in ...
Regina Nova Indradewi   +2 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The Relationship of Clean and Healthy Living Behavior and the Incidence of Malaria: Systematic Review

open access: yesJurnal Ilmiah Kesehatan
Malaria is a tropical disease caused by the bite of the Anopheles mosquito. Malaria is an infectious disease that is of global concern. This disease still often causes extraordinary events.
Rusni   +3 more
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Investigating satiety for healthy weight : Appetite control

open access: yes, 2013
Modulating feelings of hunger and satiety could be a promising approach in weight management. TNO Food & Nutrition offers advanced assessment tools to support the development of food products that help address issues of overweight and underweight.
Burgering, M.J.M.
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Towards Healthy and Sustainable Human Settlement: The Ecological and Cultural Connation of Landsenses

open access: yesLand
The construction of a healthy and sustainable living environment requires a systematic integration of multidimensional elements such as the environment, society, and economy [...]
Jiang Liu, Yuhan Shao, Xinchen Hong
doaj   +1 more source

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