A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento +3 more
wiley +1 more source
Healthy aging: how does a multidimensional construct of functional ability predict objective and subjective outcomes? [PDF]
Gbessemehlan A +4 more
europepmc +1 more source
Objectives There is growing interest in evaluating new strategies to delay or prevent post‐traumatic osteoarthritis (PTOA) in individuals who have sustained anterior cruciate ligament (ACL) injury. This study sought to determine characteristics of potential treatments that are acceptable to patients with ACL injury.
Kevin Kennedy +9 more
wiley +1 more source
Objective A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)
Shivani Garg +20 more
wiley +1 more source
Nourishing minds: the connection between healthy eating and academic success in higher education. [PDF]
Weathington J +4 more
europepmc +1 more source
New Onset of Fibromyalgia After Exposure to a Combat Environment: A Longitudinal Cohort Study
Objective Traumatic life events are hypothesized to be triggers for the onset of fibromyalgia. Posttraumatic stress disorder (PTSD) is a common comorbidity of fibromyalgia. However, limited prospective data are available on the development of fibromyalgia after exposure to high‐magnitude stress.
Jay B. Higgs +15 more
wiley +1 more source
The influence mechanisms of living environment on the physical and mental health of Chinese older adults: a cross-sectional exploration based on CLASS 2023. [PDF]
Wu Y.
europepmc +1 more source
Development of the physical education knowledge questionnaire-Spain (PEKQ-S): feasibility, validity and reliability for Spanish children aged 6-12 years. [PDF]
Pastor-Cisneros R +3 more
europepmc +1 more source
Reflecting on a decade of action: a review of select indicators for the Israel National Program for Active and Healthy Living-Efsharibari, 2011-2022. [PDF]
Levi S +3 more
europepmc +1 more source

