Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova +9 more
wiley +1 more source
The diversity of factors influencing human digestive microbiota in healthy adults and their interaction: a scoping review. [PDF]
Pérez-Llano B +2 more
europepmc +1 more source
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau +11 more
wiley +1 more source
Effects of Different Living Environments on Intestinal Flora in Patients With Schistosoma Japonicum-Induced Liver Fibrosis. [PDF]
Fan X, Zhou C, Zhang P, Ming Y.
europepmc +1 more source
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian +6 more
wiley +1 more source
Urban Indian young adults' perceptions of a healthy lifestyle and its associated factors: a multi-city qualitative inquiry using thematic analysis. [PDF]
Rathi N +7 more
europepmc +1 more source
Sociodemographic Inequalities in Healthy Food Consumption Markers Among Older Adults Receiving Primary Health Care in Roraima, Brazil. [PDF]
Ribeiro GJS +5 more
europepmc +1 more source
Age-Friendly Environments for Healthy Ageing in Place: Refinement of a Multidimensional Index and Regional Disparities in South Korea. [PDF]
Kim M.
europepmc +1 more source
High altitude pulmonary hypertension: overlap with other types of pulmonary hypertension and implications for treatment. [PDF]
Forbes LM, Lahm T.
europepmc +1 more source
A Multinational Survey: The Impact of Living With Obesity on Well-Being: A Plain Language Summary. [PDF]
Cernica C, Hahn-Pedersen JH, Zvenyach T.
europepmc +1 more source

