Results 81 to 90 of about 9,050,975 (280)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
, 2013 Helping Local People and Local Communities create a Healthier Environment The healthy gardening project is a ten week programme which runs in community gardens/allotments throughout the county in partnership with community development projects.
Healthy Food For All
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Healthy Valleys : reversing decline in eight rural communities [PDF]
, 2007 Healthy Valleys is a community focused health improvement initiative and our operating principles are our strength – we adopt a community development approach, we are flexible, responsive to communities, effective and innovative.
Coburn, Annette, Wallace, David
core +4 more sources
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
LandThe construction of a healthy and sustainable living environment requires a systematic integration of multidimensional elements such as the environment, society, and economy [...]
Jiang Liu, Yuhan Shao, Xinchen Hong
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Investigating satiety for healthy weight : Appetite control
, 2013 Modulating feelings of hunger and satiety could be a promising approach in weight management. TNO Food & Nutrition offers advanced assessment tools to support the development of food products that help address issues of overweight and underweight.
Burgering, M.J.M.
core
The Role of Government To Build Eco Community
E3S Web of Conferences, 2018 As stated in Article 28 H Consitution on Republic of Indonesia 1945, that every person has rights of good and healthy environment, medical service. The needs of healthy environment in neighborhood is highly demand in a few years. People starts to realize
Putrijanti Aju
doaj +1 more source