Results 101 to 110 of about 818,795 (308)
Arthritis Care &Research, EarlyView.Objective We developed a novel electronic health record sidecar application to visualize key rheumatoid arthritis (RA) outcomes, including disease activity, physical function, and pain, via a patient‐facing graphical interface designed for use during outpatient visits (“RA PRO dashboard”).
Gabriela Schmajuk +16 more
wiley +1 more source
Associations of Sleep and Shift Work With Osteoarthritis Risk
Arthritis Care &Research, EarlyView.Objective Daily rhythms may be critical for maintaining homeostasis of joint tissues. We aimed to investigate the relationships among circadian clock disruption, sleep, and osteoarthritis (OA) risk in humans. Methods In the UK Biobank, a prospective 500,000–person cohort, we evaluated associations among sleep duration, sleeplessness/insomnia, and shift
Elizabeth L. Yanik +5 more
wiley +1 more source
Biomolecules & Biomedicine, 2004 Angiotensin converting enzyme (ACE) plays an important role in blood pressure regulation not only in the state of rest, but also during physical exercise. The aim of this study was to estimate the serum ACE activity in response to acute dynamic exercise.
Emina Nakać-Ićindić +5 more
doaj +1 more source
Dose related pharmacokinetics of ofloxacin in healthy volunteers [PDF]
, 2002 OBJECTIVE: To evaluate the pharmacokinetic profile of ofloxacin in healthy volunteers after single oral doses of 600 and 800 mg. DESIGN: Seven healthy volunteers were administered 600 and 800 mg of ofloxacin on two occasions with an interval of one ...
Gurumurthy, P +3 more
core
Pharmacokinetics of Mezlocillin in Healthy Volunteers [PDF]
Antimicrobial Agents and Chemotherapy, 1978 Mezlocillin in doses of 1.0, 2.0, and 5.0 g and carbenicillin in doses of 2.0 g were given as bolus injections intravenously to 10 healthy volunteers. For mezlocillin, dose-dependent pharmacokinetics was detected. This is reflected by a more than proportional rise in serum concentrations and a decreased total body clearance as doses were increased. Per
openaire +2 more sources
Arthritis Care &Research, Accepted Article.Introduction Rheumatic and musculoskeletal diseases(RMDs) are leading causes of physical disability, necessitating support with activities of daily living(ADLs). This study describes social care received by patients with RMDs in two disperate regions of England: Salford(urban) and Norfolk(rural).
Mehreen Somro +6 more
wiley +1 more source
Arthritis Care &Research, Accepted Article.Objective To support high‐quality, patient‐centered care for systemic lupus erythematosus (SLE), the American College of Rheumatology (ACR) developed evidence‐based measures incorporating clinical and patient‐reported outcomes measures (PROMs). Using the Consolidated Framework for Implementation Research (CFIR), we conducted semi‐structured interviews ...
Catherine Nasrallah +13 more
wiley +1 more source
Pharmacokinetic and safety evaluation of MB12066, an NQO1 substrate
Drug Design, Development and Therapy, 2017 Hae Won Lee,1,* Sook Jin Seong,1,* Boram Ohk,1,2 Woo Youl Kang,1,2 Mi-Ri Gwon,1 Bo Kyung Kim,1,2 Hyun-Ju Kim,3 Young-Ran Yoon1,2 1Clinical Trial Center, Kyungpook National University Hospital, 2Department of Biomedical Science, BK21 Plus KNU Bio-Medical
Lee HW +7 more
doaj
BiomedicinesBackground/Objectives: The development of blood tests for the early detection of individual predisposition to socially significant diseases remains a pressing issue.
Alexey S. Kononikhin +12 more
doaj +1 more source
Effect of yoga on heart rate and blood pressure and its clinical significance [PDF]
International Journal of Biological and Medical Research, 2011 The cardiovascular morbidity is increasing in India in recent years. The present study was done to know the effect of yoga on heart rate and blood pressure in healthy volunteers above the age of 40 years.
Indla Devasena, Pandurang Narhare
doaj