Results 71 to 80 of about 1,011,375 (291)

Retrospective Grid Cells in the Medial Entorhinal Cortex Encode Past Paths During Spatial Navigation

open access: yesAdvanced Science, EarlyView.
Retrospective grid cells are identified in the medial entorhinal cortex, with spatial firing patterns that become most grid‐like when activity is projected onto recently traversed locations. Their coding loses spatial precision in darkness and is disrupted during assisted movement, indicating that entorhinal representations incorporate recent path ...
Ruojin Liu   +10 more
wiley   +1 more source

A Molecularly Defined Midbrain Circuit Mechanism for Sound‐Driven Defensive Behavior and Anxiety

open access: yesAdvanced Science, EarlyView.
Schematic diagram showing the Cbln2+ ICx–dPAG circuit for sound‐driven defensive and anxiety‐like behaviors. ABSTRACT The innate defense behaviors in response to threatening sounds play a fundamental role in survival. However, the neural circuits that detect threat‐relevant auditory cues and transform them into defensive behaviors remain poorly defined.
Jie Cao   +8 more
wiley   +1 more source

Commission on the Deaf and Hearing Impaired

open access: yes, 2014
Updated irregularly; Began in 2002?; Title from home page (publisher's Web site, viewed Aug. 28, 2012).; At head of title: State of Connecticut.; Official website of the Connecticut Commission on the Deaf and Hearing Impaired.

core  

Galactokinase 1 Positively Regulates Mitochondrial Respiration by Phosphorylating TIMM13 as a Protein Kinase

open access: yesAdvanced Science, EarlyView.
GALK1 acts as a protein kinase beyond the phosphorylation of galactose. GALK1 phosphorylates TIMM13 at Y73 in the cytoplasm. This phosphorylation prevents premature oxidative folding of TIMM13 and ensures its entrance into the intermembrane space of mitochondrion, positively regulating mitochondrial respiration.
Chang Woo Ko   +5 more
wiley   +1 more source

Commission on the Deaf and Hearing Impaired

open access: yes, 2013
Updated irregularly; Began in 2002?; Title from home page (publisher's Web site, viewed Aug. 28, 2012).; At head of title: State of Connecticut.; Official website of the Connecticut Commission on the Deaf and Hearing Impaired.

core  

WFS1 Deficiency Impairs PIAS4‐Associated SUMOylation and Increases Ubiquitin‐Mediated Spermatogenesis‐Related Protein Degradation Leading to Testicular Male Infertility

open access: yesAdvanced Science, EarlyView.
The findings establish a critical role for WFS1 in human male fertility. Mechanistically, WFS1 interacts with PIAS4 to promote the SUMOylation of key spermatogenesis‐associated proteins, which in turn competitively inhibits their K48‐linked ubiquitin‐mediated degradation during spermatogenesis.
Yunchuan Tian   +14 more
wiley   +1 more source

Hearing in 44-45 year olds with m.1555A > G, a genetic mutation predisposing to aminoglycoside-induced deafness: a population based cohort study. [PDF]

open access: yes, 2012
Background The mitochondrial DNA mutation m.1555A>G predisposes to permanent idiosyncratic aminoglycoside-induced deafness that is independent of dose.
Pearce, K   +9 more
core   +1 more source

Disrupted Top‐Down Modulation as a Mechanism of Impaired Multisensory Processing in Autistic Children

open access: yesAdvanced Science, EarlyView.
In this work, we show that multisensory integration in autistic children is characterized by attenuated ERP responses and α‐band desynchronization, together with reduced theta‐band communication between parieto‐occipital and frontal regions. The intermediate neural profile observed in unaffected siblings raises the possibility that altered cortical ...
Theo Vanneau   +3 more
wiley   +1 more source

The effect of dialect variation and hearing aid compression type on speech recognition in hearing impaired listeners [PDF]

open access: yes, 2011
It is well established that normal hearing listeners presented with speech spoken in an unfamiliar dialect demonstrate a reduction in understanding abilities.
Schumacher, Jennifer
core   +1 more source

Profile of Patients of the Auditory Health of the State of Santa Catarina Served at HU-UFSC

open access: yesInternational Archives of Otorhinolaryngology, 2011
Introduction: Hearing is one of the essential functions for the development of language and its deficiency may lead to several consequences. Objective: To describe the profile of patients of the Hearing Health Program of the State of Santa Catarina ...
Dimatos, Oscar Cardoso   +5 more
doaj  

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