Results 121 to 130 of about 2,157,151 (305)

Deciphering and Targeting the Schwannoma‐Neuron‐Macrophage Crosstalk for the Treatment of Schwannomatosis and Associated Pain

open access: yesAdvanced Science, EarlyView.
We established patient‐derived SWN cell lines and orthotopic PDX models that recapitulate patient pain phenotypes, alongside a novel intravital DRG imaging platform to track macrophage infiltration and neuronal pain responses. Using these models, we define HMGB1–CCL2–IL‐6 signaling crosstalk driving pain and identify EGF signaling as a key regulator of
Zhenzhen Yin   +17 more
wiley   +1 more source

Prevalence of somatosensory tinnitus in individuals with tinnitus

open access: yesThe Egyptian Journal of Otolaryngology
Background Somatosensory tinnitus is a form of tinnitus that can be influenced or triggered by sensory, motor, and visual-motor systems. This study aimed to estimate the prevalence of somatosensory tinnitus in individuals with tinnitus using a rapid ...
Manya Fangaria   +6 more
doaj   +1 more source

Effects of deafness on acoustic characteristics of American English tense/lax vowels in maternal speech to infants [PDF]

open access: yes, 2012
Recent studies have demonstrated that mothers exaggerate phonetic properties of infant-directed (ID) speech. However, these studies focused on a single acoustic dimension (frequency), whereas speech sounds are composed of multiple acoustic cues. Moreover,
Bergeson, Tonya R.   +1 more
core   +1 more source

Ultrasound Modulation of Visual Circuits in Mice Independent of Auditory Confound

open access: yesAdvanced Science, EarlyView.
In this study, Qiu et al. found that low‐intensity ultrasound can directly activate sparse ultrasound‐sensitive neurons (UNs) in the primary visual cortex (V1) of deafened mice. The proportion of these sparse UNs is pressure‐dependent. Furthermore, ultrasound modulates visual circuitry with distinct excitatory and inhibitory effects.
Jiaru He   +8 more
wiley   +1 more source

Non-Musicians Experience Early Aging in Speech Perception in Noise Abilities Compared to Musicians

open access: yesJournal of Otology
BackgroundResearch has shown that musicians outperform non-musicians in speech perception in noise (SPiN) tasks. However, it remains unclear whether the advantages of musical training are substantial enough to slow down the decline in SPiN performance ...
Kruthika. S., Ajith Kumar Uppunda
doaj   +1 more source

In Situ X‐Ray Tomography and Acoustic Emission Monitoring of Damage Evolution in C/C‐SiC Composites Fabricated by Liquid Silicon Infiltration

open access: yesAdvanced Science, EarlyView.
This study investigates how the internal structure of fiber‐reinforced ceramic composites affects their resistance to damage. By combining 3D X‐ray imaging with acoustic emission monitoring during mechanical testing, it reveals how silicon distribution influences crack formation.
Yang Chen   +7 more
wiley   +1 more source

SKOOTS: Skeleton‐Oriented Object Segmentation for Mitochondria in High‐Resolution Cochlear EM Datasets

open access: yesAdvanced Science, EarlyView.
Skeleton‐oriented object segmentation (SKOOTS) introduces a new strategy for 3D mitochondrial instance segmentation by predicting explicit skeletons rather than relying on boundary cues. This approach enables robust analysis of densely packed organelles in large FIB‐SEM datasets.
Christopher J. Buswinka   +3 more
wiley   +1 more source

The Importance of Hearing Screening and Central Auditory Processing in School-Aged Children

open access: yesChildren
Background/Objectives: The aim of the study was to evaluate the prevalence of undiagnosed hearing impairment or central auditory processing disorders in children from I and VIII grades of primary schools in Warsaw.
Piotr Henryk Skarżyński   +5 more
doaj   +1 more source

Restoring Iron Homeostasis via Smoothened Inhibition: A Novel Strategy Against Hearing Loss

open access: yesAdvanced Science, EarlyView.
 . ABSTRACT Sensorineural hearing loss (SNHL) induced by noise or aminoglycoside antibiotics is a significant public health concern without any FDA‐approved pharmaceutical therapies. Dysregulation of iron homeostasis and its subsequently induced ferroptosis has increasingly been identified as a key mechanism underlying cochlear hair cell (HC) damage ...
Huanyu Mao   +9 more
wiley   +1 more source

Prevalence and Severity of Tinnitus in Otosclerosis: Preliminary Findings from Validated Questionnaires

open access: yesJournal of International Advanced Otology, 2019
Piotr Henryk Skarżyński   +6 more
doaj   +1 more source

Home - About - Disclaimer - Privacy