Results 21 to 30 of about 347,698 (257)

Evaluation of impulse noise reduction in hearing aids with technical measurements and ratings of discomfort

Acta Acustica, 2023
Short, impulse-like sounds such as slamming of a door or rattle of dishes can be uncomfortable for hearing aid users. Therefore, many hearing aids provide impulse (or transient) noise reduction (INR) that should reduce loud and short sounds without ...
Husstedt Hendrik, Hilgerdenaar Wiebke, Frenz Marlitt, Denk Florian, Tchorz Jürgen   +4 more
doaj   +1 more source

Cortical inactivation by cooling in small animals

Frontiers in Systems Neuroscience, 2011
Reversible inactivation of the cortex by surface cooling is a powerful method for studying the function of a particular area. Implanted cooling cryoloops have been used to study the role of individual cortical areas in auditory processing of awake ...
Ben eCoomber, Darren eEdwards, Simon eJones, Trevor eShackleton, Jürgen eGoldschmidt, Mark eWallace, Alan ePalmer   +6 more
doaj   +1 more source

Stress Affects Central Compensation of Neural Responses to Cochlear Synaptopathy in a cGMP-Dependent Way

Frontiers in Neuroscience, 2022
In light of the increasing evidence supporting a link between hearing loss and dementia, it is critical to gain a better understanding of the nature of this relationship.
Daria Savitska, Morgan Hess, Dila Calis, Philine Marchetta, Csaba Harasztosi, Stefan Fink, Philipp Eckert, Peter Ruth, Lukas Rüttiger, Marlies Knipper, Wibke Singer   +10 more
doaj   +1 more source

Overinterpretation of high throughput sequencing data in medical genetics: first evidence against TMPRSS3/GJB2 digenic inheritance of hearing loss

Journal of Translational Medicine, 2019
Background Hearing loss (HL) is the most common disability of human senses characterized by a great allelic heterogeneity. GJB2 and TMPRSS3 are two well-known HL genes typically underlying its monogenic form.
Monika Ołdak, Urszula Lechowicz, Agnieszka Pollak, Dominika Oziębło, Henryk Skarżyński   +4 more
doaj   +1 more source

Abnormal Resting-State Quantitative Electroencephalogram in Children With Central Auditory Processing Disorder: A Pilot Study

Frontiers in Neuroscience, 2018
In this study, we showed an abnormal resting-state quantitative electroencephalogram (QEEG) pattern in children with central auditory processing disorder (CAPD).
Rafał Milner, Monika Lewandowska, Monika Lewandowska, Małgorzata Ganc, Elżbieta Włodarczyk, Diana Grudzień, Henryk Skarżyński   +6 more
doaj   +1 more source

Cellular transcription factor TFII-I represses adenovirus gene expression

Journal of Virology
To successfully replicate, viruses must overcome innate cellular antiviral responses. With human adenovirus (HAdV), a key viral repressor of cellular antiviral responses is the early protein E4ORF3. E4ORF3 relocalizes numerous cellular antiviral proteins,
Rachel L. White, Patrick Hearing
doaj   +1 more source

The Clinical Effect of Steroids for Hearing Preservation in Cochlear Implantation: Conclusions Based on Three Cochlear Implant Systems and Two Administration Regimes

Pharmaceuticals, 2022
The main aim of this study was to assess the clinical effect of steroids (dexamethasone and prednisone) on hearing preservation in patients who underwent cochlear implantation with different cochlear implant systems (Oticon®, Advanced Bionics®, Med-El®).
Magdalena B. Skarżyńska, Aleksandra Kołodziejak, Elżbieta Gos, Adam Walkowiak, Artur Lorens, Andrzej Pastuszak, Łukasz Plichta, Piotr H. Skarżyński   +7 more
doaj   +1 more source

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar, Karen Thibaudeau, Mary Mathias, Heather McDaniel, Madlen Reschke, Klaus Tenbrock, Joseph M. Parker, Amy Shapiro   +7 more
wiley   +1 more source

Incidence and Severity of Carboplatin‐Associated Hearing Loss in Children With Cancer Assessed by the SIOP Boston 2012 Ototoxicity Criteria

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Platinum‐based chemotherapy is known to cause severe and debilitating hearing loss, but unlike cisplatin, the true incidence of carboplatin‐induced hearing loss remains unclear. We evaluated functional hearing outcomes in children receiving carboplatin to determine the incidence and severity of ototoxicity. Procedure We identified a
Aniket Chawla, Sean Carter, Andrew Wood, Sandra Staffieri, Andrew Dodgshun, David D. Eisenstat, Michael Sullivan   +6 more
wiley   +1 more source

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source